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LMO7 LIM domain 7 [ Homo sapiens (human) ]

Gene ID: 4008, updated on 27-Nov-2024

Summary

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Official Symbol
LMO7provided by HGNC
Official Full Name
LIM domain 7provided by HGNC
Primary source
HGNC:HGNC:6646
See related
Ensembl:ENSG00000136153 MIM:604362; AllianceGenome:HGNC:6646
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LOMP; FBX20; LMO7b; FBXO20
Summary
This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, however, the full-length nature of some variants is not known. [provided by RefSeq, Jan 2009]
Expression
Broad expression in lung (RPKM 43.5), esophagus (RPKM 32.9) and 17 other tissues See more
Orthologs
mouse all
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Genomic context

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See LMO7 in Genome Data Viewer
Location:
13q22.2
Exon count:
40
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (75620434..75859870)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (74844083..75083598)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (76194570..76434006)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7829 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7830 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7831 Neighboring gene H3K27ac hESC enhancer GRCh37_chr13:76123825-76124385 Neighboring gene COMM domain containing 6 Neighboring gene ubiquitin C-terminal hydrolase L3 Neighboring gene ReSE screen-validated silencer GRCh37_chr13:76200739-76200877 Neighboring gene LMO7 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5403 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5404 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5405 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7834 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr13:76259126-76259626 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr13:76259627-76260127 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr13:76279181-76280380 Neighboring gene family with sequence similarity 204 member C, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7835 Neighboring gene NANOG hESC enhancer GRCh37_chr13:76377179-76377853 Neighboring gene NANOG hESC enhancer GRCh37_chr13:76399228-76399729 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5406 Neighboring gene LMO7DN intronic transcript 1 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr13:76463404-76463962 Neighboring gene LMO7 downstream neighbor Neighboring gene long intergenic non-protein coding RNA 561

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Immunoreactivity of LMO7 and other molecular markers as potential prognostic factors in oropharyngeal squamous cell carcinoma. Israelsson P, et al. BMC Oral Health, 2024 Jun 25. PMID 38918827, Free PMC Article
  2. Analysis of a human cDNA containing a tissue-specific alternatively spliced LIM domain. Putilina T, et al. Biochem Biophys Res Commun, 1998 Nov 18. PMID 9826547
  3. Association of LIM Domain 7 Gene Polymorphisms and Plasma Levels of LIM Domain 7 with Dilated Cardiomyopathy in a Chinese Population. Li C, et al. Appl Biochem Biotechnol, 2017 Jul. PMID 27988857
  4. Novel Long Non-Coding RNA (lncRNA) Transcript AL137782.1 Promotes the Migration of Normal Lung Epithelial Cells through Positively Regulating LMO7. Zhang Y, et al. Int J Mol Sci, 2023 Sep 9. PMID 37762205, Free PMC Article
  5. Role of LMO7 in cancer (Review). Zeng Q, et al. Oncol Rep, 2024 Sep. PMID 38994754, Free PMC Article

See all (141) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Role of LMO7 in cancer (Review).
    Title: Role of LMO7 in cancer (Review).
  2. Immunoreactivity of LMO7 and other molecular markers as potential prognostic factors in oropharyngeal squamous cell carcinoma.
    Title: Immunoreactivity of LMO7 and other molecular markers as potential prognostic factors in oropharyngeal squamous cell carcinoma.
  3. Exosome-transmitted circular RNA circ-LMO7 facilitates the progression of osteosarcoma by regulating miR-21-5p/ARHGAP24 axis.
    Title: Exosome-transmitted circular RNA circ-LMO7 facilitates the progression of osteosarcoma by regulating miR-21-5p/ARHGAP24 axis.
  4. Novel Long Non-Coding RNA (lncRNA) Transcript AL137782.1 Promotes the Migration of Normal Lung Epithelial Cells through Positively Regulating LMO7.
    Title: Novel Long Non-Coding RNA (lncRNA) Transcript AL137782.1 Promotes the Migration of Normal Lung Epithelial Cells through Positively Regulating LMO7.
  5. New Findings on LMO7 Transcripts, Proteins and Regulatory Regions in Human and Vertebrate Model Organisms and the Intracellular Distribution in Skeletal Muscle Cells.
    Title: New Findings on LMO7 Transcripts, Proteins and Regulatory Regions in Human and Vertebrate Model Organisms and the Intracellular Distribution in Skeletal Muscle Cells.
  6. LMO7 and LIMCH1 co-localized and co-immunoprecipitated.
    Title: LMO7 and LIMCH1 interact with LRIG proteins in lung cancer, with prognostic implications for early-stage disease.
  7. the LMO7-BRAF fusion behaves as an oncogenic alteration in papillary thyroid carcinoma
    Title: Identification of a Recurrent LMO7-BRAF Fusion in Papillary Thyroid Carcinoma.
  8. Data suggest that LMO7 interacts with MAD1 during spindle assembly phase of mitosis; LMO7 plays role in control of mitosis progression and exerts effect on spindle assembly checkpoint; LMO7 colocalizes with actin filaments; LMO7 does not colocalize with MAD1 at kinetochores in prometaphase nor at spindle poles in metaphase. (LMO7 = LIM domain only protein-7; MAD1 = mitotic spindle assembly checkpoint protein MAD1)
    Title: LMO7 exerts an effect on mitosis progression and the spindle assembly checkpoint.
  9. The miR-96-LMO7 axis may be a therapeutic target for lung cancer patients, and new diagnostic or therapeutic strategies could be developed by targeting the miR-96-LMO7 axis.
    Title: Circulating exosomal microRNA-96 promotes cell proliferation, migration and drug resistance by targeting LMO7.
  10. study suggested that the LMO7 gene may play an important role in the pathogenesis of DCM in the Han Chinese population.
    Title: Association of LIM Domain 7 Gene Polymorphisms and Plasma Levels of LIM Domain 7 with Dilated Cardiomyopathy in a Chinese Population.
Submit: New GeneRIF Correction See all GeneRIFs (15)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.
EBI GWAS Catalog
Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

HIV-1 interactions

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Protein interactions

Protein Gene Interaction Pubs
Vpr vpr HIV-1 Vpr upregulates LMO7 in HeLa cells within 12 hours of exposure PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA0858

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ubiquitin-protein transferase activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in protein ubiquitination NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of signaling IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in apical plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cell surface IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in focal adhesion HDA PubMed 
located_in mitochondrion HTP PubMed 
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ubiquitin ligase complex NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
LIM domain only protein 7
Names
F-box only protein 20
F-box protein Fbx20
LIM domain only 7 protein
LMO-7
zinc-finger domain-containing protein
NP_001293009.1
NP_001317512.1
NP_001353561.1
NP_001353562.1
NP_001353563.1
NP_001353565.1
NP_005349.3
NP_056667.2
XP_011533397.3
XP_024305127.1
XP_024305131.2
XP_047286263.1
XP_047286264.1
XP_047286265.1
XP_047286266.1
XP_047286267.1
XP_047286268.1
XP_047286270.1
XP_047286271.1
XP_047286272.1
XP_047286273.1
XP_047286274.1
XP_047286275.1
XP_047286276.1
XP_047286277.1
XP_047286278.1
XP_047286279.1
XP_047286280.1
XP_047286281.1
XP_047286282.1
XP_047286283.1
XP_047286284.1
XP_047286285.1
XP_047286286.1
XP_047286287.1
XP_047286289.1
XP_047286290.1
XP_047286291.1
XP_047286292.1
XP_047286293.1
XP_047286294.1
XP_047286295.1
XP_047286296.1
XP_047286297.1
XP_047286298.1
XP_047286299.1
XP_047286300.1
XP_047286301.1
XP_047286302.1
XP_047286303.1
XP_047286304.1
XP_047286305.1
XP_047286306.1
XP_047286307.1
XP_047286308.1
XP_047286309.1
XP_054230496.1
XP_054230497.1
XP_054230498.1
XP_054230499.1
XP_054230500.1
XP_054230501.1
XP_054230502.1
XP_054230503.1
XP_054230504.1
XP_054230505.1
XP_054230506.1
XP_054230507.1
XP_054230508.1
XP_054230509.1
XP_054230510.1
XP_054230511.1
XP_054230512.1
XP_054230513.1
XP_054230514.1
XP_054230515.1
XP_054230516.1
XP_054230517.1
XP_054230518.1
XP_054230519.1
XP_054230520.1
XP_054230521.1
XP_054230522.1
XP_054230523.1
XP_054230524.1
XP_054230525.1
XP_054230526.1
XP_054230527.1
XP_054230528.1
XP_054230529.1
XP_054230530.1
XP_054230531.1
XP_054230532.1
XP_054230533.1
XP_054230534.1
XP_054230535.1
XP_054230536.1
XP_054230537.1
XP_054230538.1
XP_054230539.1
XP_054230540.1
XP_054230541.1
XP_054230542.1
XP_054230543.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001306080.2 → NP_001293009.1  LIM domain only protein 7 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) is alternatively spliced at the 5' end, and contains two additional internal coding exons, compared to transcript variant 1. The encoded isoform (3) has a distinct N-terminus and is longer than isoform 1.
    Source sequence(s)
    AF144237, AF330045, AL137782, DA313248, FJ711162
    Consensus CDS
    CCDS81773.1
    UniProtKB/TrEMBL
    F8J2B5, F8WD26
    Related
    ENSP00000366757.4, ENST00000377534.8
    Conserved Domains (6) summary
    cd00014
    Location:17 → 129
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00136
    Location:1003 → 1070
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
    cd08368
    Location:1562 → 1620
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam15949
    Location:588 → 734
    DUF4757; Domain of unknown function (DUF4757)
    cd16269
    Location:1218 → 1229
    GBP_C; coiled coil [structural motif]
    cl20817
    Location:1175 → 1231
    GBP_C; Guanylate-binding protein, C-terminal domain

  2. NM_001330583.1 → NP_001317512.1  LIM domain only protein 7 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in an isoform (4) with a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AA777749, AF144237, AF330045, AL137782, DA438537, FJ711162
    Consensus CDS
    CCDS81774.1
    UniProtKB/TrEMBL
    A0A8V8TKQ1, E9PMT2
    Related
    ENSP00000317802.8, ENST00000321797.12
    Conserved Domains (5) summary
    cd00136
    Location:770 → 837
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
    cd08368
    Location:1329 → 1387
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam15949
    Location:355 → 501
    DUF4757; Domain of unknown function (DUF4757)
    cd16269
    Location:985 → 996
    GBP_C; coiled coil [structural motif]
    cl20817
    Location:942 → 998
    GBP_C; Guanylate-binding protein, C-terminal domain

  3. NM_001366632.2 → NP_001353561.1  LIM domain only protein 7 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL137121, AL137782, AL359392
    Consensus CDS
    CCDS53876.1
    UniProtKB/TrEMBL
    A0A0A0MTE2, A0A8V8TKQ1
    Related
    ENSP00000513106.1, ENST00000605961.2
    Conserved Domains (5) summary
    cd00136
    Location:770 → 837
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
    cd16269
    Location:985 → 996
    GBP_C; coiled coil [structural motif]
    pfam15949
    Location:355 → 502
    DUF4757; Domain of unknown function (DUF4757)
    cl20817
    Location:942 → 998
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl26511
    Location:943 → 1101
    Neuromodulin_N; Gap junction protein N-terminal region

  4. NM_001366633.2 → NP_001353562.1  LIM domain only protein 7 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AL137121, AL137782, AL359392
    UniProtKB/TrEMBL
    F8J2B5
    Conserved Domains (5) summary
    cd00136
    Location:961 → 1028
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
    cd16269
    Location:1176 → 1187
    GBP_C; coiled coil [structural motif]
    pfam15949
    Location:546 → 693
    DUF4757; Domain of unknown function (DUF4757)
    cl20817
    Location:1133 → 1189
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl26511
    Location:1134 → 1292
    Neuromodulin_N; Gap junction protein N-terminal region

  5. NM_001366634.2 → NP_001353563.1  LIM domain only protein 7 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL137121, AL137782, AL359392
    UniProtKB/TrEMBL
    A0A8V8TKQ1
    Conserved Domains (6) summary
    cd00136
    Location:676 → 743
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
    cd08368
    Location:1235 → 1293
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    cd16269
    Location:891 → 902
    GBP_C; coiled coil [structural motif]
    pfam15949
    Location:261 → 408
    DUF4757; Domain of unknown function (DUF4757)
    cl20817
    Location:848 → 904
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl26511
    Location:849 → 1007
    Neuromodulin_N; Gap junction protein N-terminal region

  6. NM_001366636.2 → NP_001353565.1  LIM domain only protein 7 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL137121, AL137782, AL359392
    UniProtKB/TrEMBL
    A0A8V8TKQ1
    Conserved Domains (6) summary
    cd00136
    Location:676 → 743
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
    cd08368
    Location:1235 → 1293
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    cd16269
    Location:891 → 902
    GBP_C; coiled coil [structural motif]
    pfam15949
    Location:261 → 408
    DUF4757; Domain of unknown function (DUF4757)
    cl20817
    Location:848 → 904
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl26511
    Location:849 → 1007
    Neuromodulin_N; Gap junction protein N-terminal region

  7. NM_005358.5 → NP_005349.3  LIM domain only protein 7 isoform 1

    See identical proteins and their annotated locations for NP_005349.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AA777749, AB020665, AF330045, AL137244, AW805522, DB064574
    Consensus CDS
    CCDS9454.1
    UniProtKB/TrEMBL
    A0A1P7ZIM8
    Related
    ENSP00000342112.4, ENST00000341547.8
    Conserved Domains (6) summary
    cd00014
    Location:74 → 181
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00136
    Location:721 → 788
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
    cd08368
    Location:1280 → 1338
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam15949
    Location:294 → 452
    DUF4757; Domain of unknown function (DUF4757)
    cd16269
    Location:936 → 947
    GBP_C; coiled coil [structural motif]
    cl20817
    Location:893 → 949
    GBP_C; Guanylate-binding protein, C-terminal domain

  8. NM_015842.2 → NP_056667.2  LIM domain only protein 7 isoform 2

    See identical proteins and their annotated locations for NP_056667.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) is alternatively spliced at the 5' and 3' ends, and contains two additional internal coding exons, compared to transcript variant 1. The encoded isoform (2) has distinct N- and C-termini, and is longer than isoform 1.
    Source sequence(s)
    AA777749, AB020665, AF330045, AK055465, AW805522, DB064574, DB227898
    Consensus CDS
    CCDS53876.1
    UniProtKB/TrEMBL
    A0A0A0MTE2, A0A8V8TKQ1
    Related
    ENSP00000433352.1, ENST00000465261.6
    Conserved Domains (5) summary
    cd00136
    Location:770 → 837
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
    cd16269
    Location:985 → 996
    GBP_C; coiled coil [structural motif]
    pfam15949
    Location:355 → 502
    DUF4757; Domain of unknown function (DUF4757)
    cl20817
    Location:942 → 998
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl26511
    Location:943 → 1101
    Neuromodulin_N; Gap junction protein N-terminal region

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    75620434..75859870
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047430323.1 → XP_047286279.1  LIM domain only protein 7 isoform X17

  2. XM_047430329.1 → XP_047286285.1  LIM domain only protein 7 isoform X20

  3. XM_047430352.1 → XP_047286308.1  LIM domain only protein 7 isoform X44

  4. XM_047430307.1 → XP_047286263.1  LIM domain only protein 7 isoform X1

  5. XM_047430308.1 → XP_047286264.1  LIM domain only protein 7 isoform X2

  6. XM_047430310.1 → XP_047286266.1  LIM domain only protein 7 isoform X4

  7. XM_047430309.1 → XP_047286265.1  LIM domain only protein 7 isoform X3

  8. XM_047430311.1 → XP_047286267.1  LIM domain only protein 7 isoform X5

  9. XM_047430312.1 → XP_047286268.1  LIM domain only protein 7 isoform X6

  10. XM_047430316.1 → XP_047286272.1  LIM domain only protein 7 isoform X9

  11. XM_047430317.1 → XP_047286273.1  LIM domain only protein 7 isoform X10

    UniProtKB/TrEMBL
    A0A0A0MTE2

  12. XM_047430320.1 → XP_047286276.1  LIM domain only protein 7 isoform X13

  13. XM_024449359.2 → XP_024305127.1  LIM domain only protein 7 isoform X14

    UniProtKB/TrEMBL
    A0A8V8TKQ1
    Conserved Domains (4) summary
    cd00136
    Location:676 → 743
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
    cd16269
    Location:918 → 929
    GBP_C; coiled coil [structural motif]
    pfam17380
    Location:878 → 1033
    DUF5401; Family of unknown function (DUF5401)
    cl20817
    Location:875 → 931
    GBP_C; Guanylate-binding protein, C-terminal domain

  14. XM_047430321.1 → XP_047286277.1  LIM domain only protein 7 isoform X15

  15. XM_047430322.1 → XP_047286278.1  LIM domain only protein 7 isoform X16

  16. XM_047430324.1 → XP_047286280.1  LIM domain only protein 7 isoform X18

    Related
    ENSP00000388955.1, ENST00000447038.5

  17. XM_011535095.3 → XP_011533397.3  LIM domain only protein 7 isoform X22

  18. XM_047430333.1 → XP_047286289.1  LIM domain only protein 7 isoform X24

  19. XM_047430334.1 → XP_047286290.1  LIM domain only protein 7 isoform X25

  20. XM_047430331.1 → XP_047286287.1  LIM domain only protein 7 isoform X23

  21. XM_047430337.1 → XP_047286293.1  LIM domain only protein 7 isoform X28

  22. XM_047430338.1 → XP_047286294.1  LIM domain only protein 7 isoform X29

  23. XM_047430330.1 → XP_047286286.1  LIM domain only protein 7 isoform X21

  24. XM_047430335.1 → XP_047286291.1  LIM domain only protein 7 isoform X26

  25. XM_047430336.1 → XP_047286292.1  LIM domain only protein 7 isoform X27

  26. XM_047430340.1 → XP_047286296.1  LIM domain only protein 7 isoform X31

  27. XM_047430343.1 → XP_047286299.1  LIM domain only protein 7 isoform X34

  28. XM_047430315.1 → XP_047286271.1  LIM domain only protein 7 isoform X8

  29. XM_047430319.1 → XP_047286275.1  LIM domain only protein 7 isoform X12

  30. XM_047430341.1 → XP_047286297.1  LIM domain only protein 7 isoform X32

  31. XM_047430345.1 → XP_047286301.1  LIM domain only protein 7 isoform X37

  32. XM_047430347.1 → XP_047286303.1  LIM domain only protein 7 isoform X39

    Related
    ENSP00000435296.3, ENST00000525107.7

  33. XM_047430350.1 → XP_047286306.1  LIM domain only protein 7 isoform X42

  34. XM_047430344.1 → XP_047286300.1  LIM domain only protein 7 isoform X35

  35. XM_047430327.1 → XP_047286283.1  LIM domain only protein 7 isoform X17

  36. XM_047430326.1 → XP_047286282.1  LIM domain only protein 7 isoform X17

  37. XM_047430353.1 → XP_047286309.1  LIM domain only protein 7 isoform X45

  38. XM_047430314.1 → XP_047286270.1  LIM domain only protein 7 isoform X7

  39. XM_047430318.1 → XP_047286274.1  LIM domain only protein 7 isoform X11

  40. XM_047430325.1 → XP_047286281.1  LIM domain only protein 7 isoform X19

  41. XM_047430339.1 → XP_047286295.1  LIM domain only protein 7 isoform X30

  42. XM_047430342.1 → XP_047286298.1  LIM domain only protein 7 isoform X33

  43. XM_047430346.1 → XP_047286302.1  LIM domain only protein 7 isoform X38

  44. XM_047430348.1 → XP_047286304.1  LIM domain only protein 7 isoform X40

  45. XM_047430351.1 → XP_047286307.1  LIM domain only protein 7 isoform X43

  46. XM_024449363.2 → XP_024305131.2  LIM domain only protein 7 isoform X36

    Related
    ENSP00000431129.1, ENST00000526202.5

  47. XM_047430349.1 → XP_047286305.1  LIM domain only protein 7 isoform X41

  48. XM_047430328.1 → XP_047286284.1  LIM domain only protein 7 isoform X17

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    74844083..75083598
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054374537.1 → XP_054230512.1  LIM domain only protein 7 isoform X17

  2. XM_054374543.1 → XP_054230518.1  LIM domain only protein 7 isoform X20

  3. XM_054374567.1 → XP_054230542.1  LIM domain only protein 7 isoform X44

  4. XM_054374521.1 → XP_054230496.1  LIM domain only protein 7 isoform X1

  5. XM_054374522.1 → XP_054230497.1  LIM domain only protein 7 isoform X2

  6. XM_054374524.1 → XP_054230499.1  LIM domain only protein 7 isoform X4

  7. XM_054374523.1 → XP_054230498.1  LIM domain only protein 7 isoform X3

  8. XM_054374525.1 → XP_054230500.1  LIM domain only protein 7 isoform X5

  9. XM_054374526.1 → XP_054230501.1  LIM domain only protein 7 isoform X6

  10. XM_054374529.1 → XP_054230504.1  LIM domain only protein 7 isoform X9

  11. XM_054374530.1 → XP_054230505.1  LIM domain only protein 7 isoform X10

    UniProtKB/TrEMBL
    A0A0A0MTE2

  12. XM_054374533.1 → XP_054230508.1  LIM domain only protein 7 isoform X13

  13. XM_054374534.1 → XP_054230509.1  LIM domain only protein 7 isoform X14

  14. XM_054374535.1 → XP_054230510.1  LIM domain only protein 7 isoform X15

  15. XM_054374536.1 → XP_054230511.1  LIM domain only protein 7 isoform X16

  16. XM_054374538.1 → XP_054230513.1  LIM domain only protein 7 isoform X18

  17. XM_054374545.1 → XP_054230520.1  LIM domain only protein 7 isoform X22

  18. XM_054374547.1 → XP_054230522.1  LIM domain only protein 7 isoform X24

  19. XM_054374548.1 → XP_054230523.1  LIM domain only protein 7 isoform X25

  20. XM_054374546.1 → XP_054230521.1  LIM domain only protein 7 isoform X23

  21. XM_054374551.1 → XP_054230526.1  LIM domain only protein 7 isoform X28

  22. XM_054374552.1 → XP_054230527.1  LIM domain only protein 7 isoform X29

  23. XM_054374544.1 → XP_054230519.1  LIM domain only protein 7 isoform X21

  24. XM_054374549.1 → XP_054230524.1  LIM domain only protein 7 isoform X26

  25. XM_054374550.1 → XP_054230525.1  LIM domain only protein 7 isoform X27

  26. XM_054374554.1 → XP_054230529.1  LIM domain only protein 7 isoform X31

  27. XM_054374557.1 → XP_054230532.1  LIM domain only protein 7 isoform X34

  28. XM_054374528.1 → XP_054230503.1  LIM domain only protein 7 isoform X8

  29. XM_054374532.1 → XP_054230507.1  LIM domain only protein 7 isoform X12

  30. XM_054374555.1 → XP_054230530.1  LIM domain only protein 7 isoform X32

  31. XM_054374560.1 → XP_054230535.1  LIM domain only protein 7 isoform X37

  32. XM_054374562.1 → XP_054230537.1  LIM domain only protein 7 isoform X39

  33. XM_054374565.1 → XP_054230540.1  LIM domain only protein 7 isoform X42

  34. XM_054374558.1 → XP_054230533.1  LIM domain only protein 7 isoform X35

  35. XM_054374541.1 → XP_054230516.1  LIM domain only protein 7 isoform X17

  36. XM_054374540.1 → XP_054230515.1  LIM domain only protein 7 isoform X17

  37. XM_054374564.1 → XP_054230539.1  LIM domain only protein 7 isoform X41

  38. XM_054374527.1 → XP_054230502.1  LIM domain only protein 7 isoform X7

  39. XM_054374568.1 → XP_054230543.1  LIM domain only protein 7 isoform X45

  40. XM_054374531.1 → XP_054230506.1  LIM domain only protein 7 isoform X11

  41. XM_054374539.1 → XP_054230514.1  LIM domain only protein 7 isoform X19

  42. XM_054374553.1 → XP_054230528.1  LIM domain only protein 7 isoform X30

  43. XM_054374556.1 → XP_054230531.1  LIM domain only protein 7 isoform X33

  44. XM_054374561.1 → XP_054230536.1  LIM domain only protein 7 isoform X38

  45. XM_054374563.1 → XP_054230538.1  LIM domain only protein 7 isoform X40

  46. XM_054374566.1 → XP_054230541.1  LIM domain only protein 7 isoform X43

  47. XM_054374559.1 → XP_054230534.1  LIM domain only protein 7 isoform X36

  48. XM_054374542.1 → XP_054230517.1  LIM domain only protein 7 isoform X17

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_015843.1: Suppressed sequence

    Description
    NM_015843.1: This RefSeq was temporarily suppressed because the CDS is 5'' partial, and currently there is not sufficient data to support this transcript variant.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8WWI1.3 GenPept UniProtKB/Swiss-Prot:Q8WWI1

Gene LinkOut

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