Grd - Glycine receptor
Enables GABA-A receptor activity; GABA-gated chloride ion channel activity; and monoatomic cation channel activity. Involved in several processes, including glycinergic synaptic transmission; negative regulation of neuronal action potential; and regulation of circadian rhythm. Predicted to be located in membrane. Predicted to be part of transmembrane transporter complex. Predicted to be active in neuron projection; plasma membrane; and synapse. Human ortholog(s) of this gene implicated in bipolar disorder; depressive disorder; epilepsy (multiple); and multiple sclerosis. Orthologous to several human genes including GABRA1 (gamma-aminobutyric acid type A receptor subunit alpha1); GABRA3 (gamma-aminobutyric acid type A receptor subunit alpha3); and GABRA5 (gamma-aminobutyric acid type A receptor subunit alpha5). [provided by Alliance of Genome Resources, Nov 2024]
NCBI Orthologs
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Protein alignment
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