Eip74EF Ecdysone-induced protein 74EF [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Eip74EFprovided by FlyBase
Official Full Name: Ecdysone-induced protein 74EFprovided by FlyBase
Primary source: FLYBASE:FBgn0000567
Locus tag: Dmel_CG32180
See related: AllianceGenome:FB:FBgn0000567
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 3.3; 74EF; CG32180; CG6273; CG6285; Dmel\CG32180; E-74; e74; E74; E74-B; E74A; E74A/B; e74b; e74B; E74B; EcI; ECIP; Eip74; Eip74 A; Eip74A; Eip74E; eip74ef; eip74EF; l(3)24; l(3)neo24; mE74
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in several processes, including autophagic cell death; positive regulation of transcription by RNA polymerase II; and spermatogenesis. Located in nucleus. Is expressed in adult head; embryonic/larval salivary gland; and organism. Orthologous to human ELF1 (E74 like ETS transcription factor 1); ELF2 (E74 like ETS transcription factor 2); and ELF4 (E74 like ETS transcription factor 4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (17558672..17619325, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (17551772..17612425, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in autophagic cell death	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in autophagy	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in oogenesis	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of development, heterochronic	TAS Traceable Author Statement more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in spermatogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

Names: CG32180-PA; CG32180-PB; CG32180-PC; CG32180-PD; CG32180-PE; Ecdysone-induced prot 74EF; Ecdysone-induced-protein 74EF; Eip74EF-PA; Eip74EF-PB; Eip74EF-PC; Eip74EF-PD; Eip74EF-PE; ecdysone E74; ecdysone induced protein 74EF; ecdysone inducible protein; ecdysone-induced protein 74EF