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st scarlet [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39836, updated on 9-Dec-2024

Summary

Official Symbol
stprovided by FlyBase
Official Full Name
scarletprovided by FlyBase
Primary source
FLYBASE:FBgn0003515
Locus tag
Dmel_CG4314
See related
AllianceGenome:FB:FBgn0003515
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG4314; Dmel\CG4314; DmScarlet; ST
Summary
Enables amine transmembrane transporter activity. Involved in aminergic neurotransmitter loading into synaptic vesicle; eye pigment precursor transport; and transmembrane transport. Located in pigment granule membrane. Is expressed in Bolwig organ; Malpighian tubule main body primordium; Malpighian tubule primordium; adult head; and embryonic Malpighian tubule. Used to study neurodegenerative disease. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

Location:
73A3-73A3; 3-44 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16497651..16500460)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16490751..16493560)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene argos Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables amine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in aminergic neurotransmitter loading into synaptic vesicle IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in eye pigment precursor transport IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in eye pigment precursor transport TAS
Traceable Author Statement
more info
PubMed 
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasmic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in pigment granule membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
scarlet
Names
CG4314-PA
st-PA
NP_524108.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    16497651..16500460
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079384.5NP_524108.1  scarlet [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524108.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P45843, Q6NP00, Q6NR69, Q9VV67
    UniProtKB/TrEMBL
    S5M3P7
    Related
    FBpp0075149
    Conserved Domains (3) summary
    cd03213
    Location:66298
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:67665
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:395600
    ABC2_membrane; ABC-2 type transporter