Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

ClC-c - Chloride channel-c

Enables chloride transmembrane transporter activity. Involved in chloride transmembrane transport; endosomal lumen acidification; and renal system process. Located in early endosome and recycling endosome. Is expressed in adult head. Used to study low molecular weight proteinuria with hypercalciuric nephrocalcinosis. Human ortholog(s) of this gene implicated in Dent disease 1; Raynaud-Claes syndrome; X-linked nephrolithiasis type I; X-linked recessive hypophosphatemic rickets; and low molecular weight proteinuria with hypercalciuric nephrocalcinosis. Orthologous to several human genes including CLCN4 (chloride voltage-gated channel 4). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

How was this calculated?

genes for:

Protein alignment

Align

Download data

Download
Species Gene Architecture aa