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CG17027 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39742, updated on 4-Jan-2025

Summary

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Official Symbol
CG17027provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036553
Locus tag
Dmel_CG17027
See related
AllianceGenome:FB:FBgn0036553
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
152392_at; Dmel\CG17027; IMP
Summary
Predicted to enable inositol monophosphate 1-phosphatase activity. Predicted to be involved in inositol metabolic process and signal transduction. Predicted to be located in cytoplasm. Is expressed in embryonic Malpighian tubule and embryonic proventriculus. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG17027 in Genome Data Viewer
Location:
72C1-72C1; 3-43 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15980100..15981888)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15973200..15974988)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene brahma Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ADP ribosylation factor-like 1 Neighboring gene DNA polymerase delta subunit 1 Neighboring gene long non-coding RNA:CR45446

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The guanine exchange factor Gartenzwerg and the small GTPase Arl1 function in the same pathway with Arfaptin during synapse growth. Chang L, et al. Biol Open, 2015 Jun 26. PMID 26116655, Free PMC Article
  2. A conserved myotubularin-related phosphatase regulates autophagy by maintaining autophagic flux. Allen EA, et al. J Cell Biol, 2020 Nov 2. PMID 32915229, Free PMC Article
  3. Molecular genetic analyses of polytene chromosome region 72A-D in Drosophila melanogaster reveal a gene desert in 72D. Cooper MT, et al. PLoS One, 2011. PMID 21853143, Free PMC Article
  4. A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila. Port F, et al. Elife, 2020 Feb 13. PMID 32053108, Free PMC Article
  5. Genome-wide analysis on inbreeding effects on gene expression in Drosophila melanogaster. Kristensen TN, et al. Genetics, 2005 Sep. PMID 15944359, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables inositol monophosphate 1-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables inositol monophosphate 1-phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables inositol monophosphate 1-phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in inositol metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG17027-PA
CG17027-PB
NP_001261909.1
NP_648823.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    15980100..15981888
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001274980.1 → NP_001261909.1  uncharacterized protein Dmel_CG17027, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261909.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VUW4
    Conserved Domains (1) summary
    cd01639
    Location:12 → 259
    IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...

  2. NM_140566.3 → NP_648823.1  uncharacterized protein Dmel_CG17027, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648823.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VUW4
    Related
    FBpp0075271
    Conserved Domains (1) summary
    cd01639
    Location:12 → 259
    IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VUW4 Q9VUW4

Gene LinkOut

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