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AGO2 - Argonaute 2

Enables endoribonuclease activity, cleaving siRNA-paired mRNA; siRNA binding activity; and single-stranded RNA binding activity. Involved in several processes, including dosage compensation by hyperactivation of X chromosome; dsRNA transport; and regulatory ncRNA-mediated gene silencing. Located in neuronal ribonucleoprotein granule and nucleus. Part of RISC complex and RISC-loading complex. Is expressed in adult brain cell body rind and adult head. [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to AGO2

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Species Gene Architecture aa