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Msh6 - Msh6

Predicted to enable ATP hydrolysis activity and mismatched DNA binding activity. Involved in meiotic mismatch repair. Predicted to be part of MutSalpha complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Lynch syndrome; colorectal carcinoma; endometrial cancer; hereditary nonpolyposis colorectal cancer type 5; and mismatch repair cancer syndrome. Orthologous to human MSH6 (mutS homolog 6). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to Msh6

NCBI Orthologs

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Species Gene Architecture aa