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bmm - brummer

Enables triacylglycerol lipase activity. Involved in several processes, including lipophagy; negative regulation of sequestering of triglyceride; and triglyceride metabolic process. Located in cytosol. Is active in lipid droplet. Is expressed in several structures, including adult head; anlage in statu nascendi; central brain anlage in statu nascendi; fat body; and gut section. Used to study acquired metabolic disease and obesity. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 10; coronary artery disease; liver disease (multiple); and type 2 diabetes mellitus. Orthologous to several human genes including PNPLA2 (patatin like phospholipase domain containing 2); PNPLA3 (patatin like phospholipase domain containing 3); and PNPLA5 (patatin like phospholipase domain containing 5). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to bmm

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Species Gene Architecture aa