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CG11251 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39490, updated on 9-Dec-2024

Summary

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Official Symbol
CG11251provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036346
Locus tag
Dmel_CG11251
See related
AllianceGenome:FB:FBgn0036346
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG11251
Summary
Predicted to enable acetylpyruvate hydrolase activity. Orthologous to human FAHD2A (fumarylacetoacetate hydrolase domain containing 2A) and FAHD2B (fumarylacetoacetate hydrolase domain containing 2B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG11251 in Genome Data Viewer
Location:
70A1-70A1; 3-40 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (13088581..13089969, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (13081681..13083069, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43652 Neighboring gene long non-coding RNA:CR45749 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44554 Neighboring gene tartan

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. tartan underlies the evolution of Drosophila male genital morphology. Hagen JFD, et al. Proc Natl Acad Sci U S A, 2019 Sep 17. PMID 31484761, Free PMC Article
  2. A genome-wide RNAi screen reveals multiple regulators of caspase activation. Yi CH, et al. J Cell Biol, 2007 Nov 19. PMID 17998402, Free PMC Article
  3. Unraveling the Genetic Basis for the Rapid Diversification of Male Genitalia between Drosophila Species. Hagen JFD, et al. Mol Biol Evol, 2021 Jan 23. PMID 32931587, Free PMC Article
  4. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
  5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables acetylpyruvate hydrolase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11251-PA
NP_648632.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    13088581..13089969 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140375.3 → NP_648632.1  uncharacterized protein Dmel_CG11251 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648632.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VU50
    Related
    FBpp0075625
    Conserved Domains (2) summary
    TIGR02303
    Location:112 → 334
    HpaG-C-term; 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit
    pfam01557
    Location:135 → 333
    FAA_hydrolase; Fumarylacetoacetate (FAA) hydrolase family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VU50 Q9VU50

Gene LinkOut

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