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CG42588 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39457, updated on 4-Jan-2025

Summary

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Official Symbol
CG42588provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0260965
Locus tag
Dmel_CG42588
See related
AllianceGenome:FB:FBgn0260965
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:SD20456; BP1016; CG11008; CG32108; CG34017; Dmel\CG42588
Old locus tag
Dmel_CG11008; Dmel_CG32108; Dmel_CG34017
Summary
Predicted to be involved in transcription by RNA polymerase III. Predicted to be part of transcription factor TFIIIC complex. Is expressed in spermatozoon. Orthologous to human GTF3C2 (general transcription factor IIIC subunit 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG42588 in Genome Data Viewer
Location:
69E4-69E5; 3-39 cM
Exon count:
11
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12814254..12824650)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12807354..12817750)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Sin3A-associated protein 130 Neighboring gene uncharacterized protein Neighboring gene Splicing factor 3a subunit 2 Neighboring gene nebulosa Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Stable intronic sequence RNAs have possible regulatory roles in Drosophila melanogaster. Pek JW, et al. J Cell Biol, 2015 Oct 26. PMID 26504165, Free PMC Article
  2. Genomic signatures of experimental adaptive radiation in Drosophila. Michalak P, et al. Mol Ecol, 2019 Feb. PMID 30375065
  3. A misexpression screen to identify regulators of Drosophila larval hemocyte development. Stofanko M, et al. Genetics, 2008 Sep. PMID 18757933, Free PMC Article
  4. A computational and experimental approach to validating annotations and gene predictions in the Drosophila melanogaster genome. Yandell M, et al. Proc Natl Acad Sci U S A, 2005 Feb 1. PMID 15668397, Free PMC Article
  5. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in transcription by RNA polymerase III IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of transcription factor TFIIIC complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG42588-PA
CG42588-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    12814254..12824650
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140347.4 → NP_648604.2  uncharacterized protein Dmel_CG42588, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648604.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VU16
    Conserved Domains (2) summary
    PHA03247
    Location:11 → 541
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:2363 → 2403
    7WD40; WD40 repeat [structural motif]

  2. NM_001202159.2 → NP_001189088.1  uncharacterized protein Dmel_CG42588, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189088.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9MSL0
    Conserved Domains (2) summary
    pfam05793
    Location:825 → 1083
    TFIIF_alpha; Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
    sd00039
    Location:2338 → 2378
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9MSL0 M9MSL0
Q8MRV4 Q8MRV4
Q9VU16 Q9VU16

Gene LinkOut

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