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brd2.S bromodomain containing 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 394399, updated on 4-Jan-2025

Summary

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Official Symbol
brd2.S
Official Full Name
bromodomain containing 2 S homeolog
Primary source
Xenbase:XB-GENE-865469
Locus tag
XELAEV_18042427mg
See related
EnsemblRapid:ENSXLAG00005007962 AllianceGenome:Xenbase:XB-GENE-865469
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
fsh; nat; brd2; rnf3; fsrg1; ring3; brd2-a
Summary
Predicted to act upstream of or within chromatin organization. Predicted to be located in chromosome and nucleus. Human ortholog(s) of this gene implicated in B-cell lymphoma; B-lymphoblastic leukemia/lymphoma; juvenile myoclonic epilepsy; and photosensitivity disease. Orthologous to human BRD2 (bromodomain containing 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See brd2.S in Genome Data Viewer
Location:
chromosome: 8S
Exon count:
14
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (80765807..80779502, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (78385358..78398930, complement)

Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene retinoid X receptor beta S homeolog Neighboring gene collagen type XI alpha 2 S homeolog Neighboring gene major histocompatibility complex, class II, DM alpha S homeolog Neighboring gene HAUS augmin like complex subunit 3 gene 2 S homeolog Neighboring gene proteasome subunit beta 9 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
bromodomain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    80765807..80779502 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018233213.2 → XP_018088702.1  bromodomain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8J0TR00
    Related
    ENSXLAP00005022810.1, ENSXLAT00005023512.1

  2. XM_018233212.2 → XP_018088701.1  bromodomain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8J0TR00
    Related
    ENSXLAP00005022793.1, ENSXLAT00005023495.1

  3. XM_018233211.2 → XP_018088700.1  bromodomain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8J0TQ06

  4. XM_018233210.2 → XP_018088699.1  bromodomain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A1L8F3L2, A0A974H6B8
    Related
    ENSXLAP00005022774.1, ENSXLAT00005023476.1

  5. XM_041575225.1 → XP_041431159.1  bromodomain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8J1LPL3
    Conserved Domains (3) summary
    cd05498
    Location:223 → 324
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:490 → 554
    BET; Bromodomain extra-terminal - transcription regulation
    cl02556
    Location:1 → 60
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
Nucleotide Protein Strain
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