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CG10657 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39423, updated on 4-Jan-2025

Summary

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Official Symbol
CG10657provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036289
Locus tag
Dmel_CG10657
See related
AllianceGenome:FB:FBgn0036289
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BEST:LD32330; Dmel\CG10657
Summary
Predicted to enable phosphatidylinositol bisphosphate binding activity. Predicted to be located in endosome. Is expressed in several structures, including adult head; dorsal head epidermis; embryonic anal pad; embryonic epipharynx; and gut section. Human ortholog(s) of this gene implicated in Bothnia retinal dystrophy; Newfoundland cone-rod dystrophy; fundus albipunctatus; night blindness; and retinitis pigmentosa. Orthologous to several human genes including CLVS2 (clavesin 2) and RLBP1 (retinaldehyde binding protein 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG10657 in Genome Data Viewer
Location:
69C3-69C3; 3-38 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12491830..12497216, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12484930..12490316, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45681 Neighboring gene antisense RNA:CR45682 Neighboring gene antisense RNA:CR43868 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide transcriptional orchestration of circadian rhythms in Drosophila. Ueda HR, et al. J Biol Chem, 2002 Apr 19. PMID 11854264
  2. Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Mummery-Widmer JL, et al. Nature, 2009 Apr 23. PMID 19363474, Free PMC Article
  3. Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease. Vartiainen S, et al. Dis Model Mech, 2014 Jun. PMID 24812436, Free PMC Article
  4. A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila. Port F, et al. Elife, 2020 Feb 13. PMID 32053108, Free PMC Article
  5. Microarray analysis and organization of circadian gene expression in Drosophila. McDonald MJ, et al. Cell, 2001 Nov 30. PMID 11733057

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables phosphatidylinositol bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol bisphosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in endosome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10657-PA
retinaldehyde-binding related protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    12491830..12497216 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140322.3 → NP_648579.3  uncharacterized protein Dmel_CG10657 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648579.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95RD7, Q9VTY1
    Related
    FBpp0075707
    Conserved Domains (2) summary
    smart01100
    Location:52 → 98
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam00650
    Location:126 → 274
    CRAL_TRIO; CRAL/TRIO domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VTY1 Q9VTY1

Gene LinkOut

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