hpcal1 hippocalcin-like 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: hpcal1provided by ZNC
Official Full Name: hippocalcin-like 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1242
See related: Ensembl:ENSDARG00000022763 AllianceGenome:ZFIN:ZDB-GENE-040426-1242
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:63695
Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in regulation of signal transduction. Orthologous to human HPCAL1 (hippocalcin like 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 20

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (31231159..31252832, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (31330042..31349693, complement)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of signal transduction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: hippocalcin-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_201164.1 → NP_957458.1 hippocalcin-like protein 1

See identical proteins and their annotated locations for NP_957458.1

Status: PROVISIONAL

Source sequence(s)

BC055210

UniProtKB/TrEMBL

A0A8M2B7I6, Q7SXX4

Related

ENSDARP00000038816.3, ENSDART00000028471.5

Conserved Domains (3) summary

COG5126
Location:13 → 179

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

cd00051
Location:100 → 174

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

cl08302
Location:36 → 89

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007131.7 Reference GRCz11 Primary Assembly

Range

31231159..31252832 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005160651.5 → XP_005160708.1 hippocalcin-like protein 1 isoform X1

See identical proteins and their annotated locations for XP_005160708.1

UniProtKB/TrEMBL

A0A8M2B7I6, Q7SXX4

Related

ENSDARP00000114371.1, ENSDART00000137236.3

Conserved Domains (3) summary

COG5126
Location:13 → 179

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

cd00051
Location:100 → 174

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

cl08302
Location:36 → 89

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
XM_068215398.1 → XP_068071499.1 hippocalcin-like protein 1 isoform X1

UniProtKB/TrEMBL

A0A8M2B7I6, Q7SXX4