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romo1 reactive oxygen species modulator 1 [ Danio rerio (zebrafish) ]

Gene ID: 393770, updated on 4-Jan-2025

Summary

Official Symbol
romo1provided by ZNC
Official Full Name
reactive oxygen species modulator 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1768
See related
Ensembl:ENSDARG00000038076 AllianceGenome:ZFIN:ZDB-GENE-040426-1768
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:73345; zgc:77111
Summary
Predicted to be involved in several processes, including cellular response to reactive oxygen species; protein targeting to mitochondrion; and replicative senescence. Predicted to act upstream of or within defense response to bacterium. Predicted to be located in mitochondrion. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is expressed in several structures, including alar plate midbrain region; liver; optic tectum; optic vesicle; and retina. Orthologous to human ROMO1 (reactive oxygen species modulator 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See romo1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (50401585..50404775, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (50402366..50405556, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496022 Neighboring gene cytochrome c-1 Neighboring gene ERGIC and golgi 3 Neighboring gene myelocytomatosis oncogene homolog Neighboring gene uncharacterized LOC137495893

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Clone Names

  • MGC73345

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in cellular response to reactive oxygen species ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of cell population proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of reactive oxygen species metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein import into mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein insertion into mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in replicative senescence ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of TIM23 mitochondrial import inner membrane translocase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
reactive oxygen species modulator 1
Names
ROS modulator 1
protein MGR2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200797.4NP_957091.1  reactive oxygen species modulator 1

    See identical proteins and their annotated locations for NP_957091.1

    Status: VALIDATED

    Source sequence(s)
    BI883966, EH450114, EH509025, EH545431
    UniProtKB/Swiss-Prot
    Q6NYD1
    Related
    ENSDARP00000055509.5, ENSDART00000055510.6
    Conserved Domains (1) summary
    pfam10247
    Location:1580
    Romo1; Reactive mitochondrial oxygen species modulator 1

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    50401585..50404775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)