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vamp4 vesicle-associated membrane protein 4 [ Danio rerio (zebrafish) ]

Gene ID: 393708, updated on 9-Dec-2024

Summary

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Official Symbol
vamp4provided by ZNC
Official Full Name
vesicle-associated membrane protein 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-040625-92
See related
Ensembl:ENSDARG00000043510 AllianceGenome:ZFIN:ZDB-GENE-040625-92
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:73166; zgc:86855
Summary
Predicted to be involved in SNARE complex assembly. Predicted to act upstream of or within Golgi ribbon formation and vesicle-mediated transport. Predicted to be located in membrane. Predicted to be part of SNARE complex. Predicted to be active in trans-Golgi network. Is expressed in central nervous system. Orthologous to human VAMP4 (vesicle associated membrane protein 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See vamp4 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (14968078..15005119)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (15072037..15109139)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene methyltransferase 13, eEF1A lysine and N-terminal methyltransferase Neighboring gene inosine triphosphatase (nucleoside triphosphate pyrophosphatase) Neighboring gene myocilin Neighboring gene proline-rich coiled-coil 2C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Mother-Specific Signature in the Maternal Transcriptome Composition of Mature, Unfertilized Zebrafish Eggs. Rauwerda H, et al. PLoS One, 2016. PMID 26799215, Free PMC Article
  2. Evolution and genomic organization of muscle microRNAs in fish genomes. Nachtigall PG, et al. BMC Evol Biol, 2014 Sep 25. PMID 25253178, Free PMC Article
  3. Evolutionary evidence of tumor necrosis factor super family members in the Japanese pufferfish (Takifugu rubripes): Comprehensive genomic identification and expression analysis. Biswas G, et al. Mar Genomics, 2015 Aug. PMID 25792259
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC73166

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within Golgi ribbon formation IEA
Inferred from Electronic Annotation
more info
  
involved_in SNARE complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
vesicle-associated membrane protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001433724.1 → NP_001420653.1  vesicle-associated membrane protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    CABZ01063328, FP074855, FP102015
    UniProtKB/TrEMBL
    A0A8M1PFQ0, A0A8M3ALD9, F6P4N7, Q6IQB0

  2. NM_001433725.1 → NP_001420654.1  vesicle-associated membrane protein 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CABZ01063328, FP074855, FP102015
    UniProtKB/TrEMBL
    A0A8M1PFQ0, F6P4N7

  3. NM_200735.3 → NP_957029.3  vesicle-associated membrane protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    CABZ01063328, FP074855, FP102015
    UniProtKB/TrEMBL
    A0A8M1PFQ0, A0A8M3ALD9, F6P4N7, Q6IQB0
    Related
    ENSDARP00000063873.6, ENSDART00000063874.7

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    14968078..15005119
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009294594.4 → XP_009292869.1  vesicle-associated membrane protein 4 isoform X1

    Related
    ENSDARP00000148329.1, ENSDART00000190910.1
    Conserved Domains (2) summary
    cd15869
    Location:50 → 116
    R-SNARE_VAMP4; SNARE motif of VAMP4
    pfam00957
    Location:49 → 118
    Synaptobrevin; Synaptobrevin
Nucleotide Protein Strain
Heading Accession and Version

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