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arl3l2 ADP ribosylation factor like GTPase 3, like 2 [ Danio rerio (zebrafish) ]

Gene ID: 393692, updated on 9-Dec-2024

Summary

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Official Symbol
arl3l2provided by ZNC
Official Full Name
ADP ribosylation factor like GTPase 3, like 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1678
See related
Ensembl:ENSDARG00000015404 AllianceGenome:ZFIN:ZDB-GENE-040426-1678
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:73116
Summary
Predicted to enable GTP binding activity. Acts upstream of or within optomotor response and regulation of axon extension involved in axon guidance. Predicted to be located in centrosome. Predicted to be active in cytoplasm and microtubule cytoskeleton. Is expressed in brain; head; and visual system. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See arl3l2 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (909717..917067)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (891444..898809)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene regulator of G protein signaling 14a Neighboring gene uncharacterized LOC103912050 Neighboring gene uncharacterized LOC137487551 Neighboring gene myozenin 3a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Habenular commissure formation in zebrafish is regulated by the pineal gland-specific gene unc119c. Toyama R, et al. Dev Dyn, 2013 Sep. PMID 23749482, Free PMC Article
  2. Knockdown of unc119c results in visual impairment and early-onset retinal dystrophy in zebrafish. Rainy N, et al. Biochem Biophys Res Commun, 2016 May 13. PMID 27079236
  3. Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish. Jia D, et al. Cell Death Dis, 2022 Nov 17. PMID 36396940, Free PMC Article
  4. Transcriptome analysis of the zebrafish pineal gland. Toyama R, et al. Dev Dyn, 2009 Jul. PMID 19504458, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC73116

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within optomotor response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of axon extension involved in axon guidance IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of axon extension involved in axon guidance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ADP ribosylation factor like GTPase 3, like 2
Names
ADP-ribosylation factor-like 3, like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200719.1 → NP_957013.1  ADP ribosylation factor like GTPase 3, like 2

    See identical proteins and their annotated locations for NP_957013.1

    Status: PROVISIONAL

    Source sequence(s)
    BC059480
    UniProtKB/TrEMBL
    A0A8M1PBN5, Q6PC43
    Related
    ENSDARP00000008099.5, ENSDART00000021346.8
    Conserved Domains (1) summary
    cd04155
    Location:8 → 181
    Arl3; Arf-like 3 (Arl3) GTPase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    909717..917067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169564.5 → XP_005169621.1  ADP ribosylation factor like GTPase 3, like 2 isoform X1

    UniProtKB/TrEMBL
    A0A140LG87, A0A8M2BGU1
    Related
    ENSDARP00000142265.1, ENSDART00000172777.2
    Conserved Domains (1) summary
    cd04155
    Location:8 → 180
    Arl3; Arf-like 3 (Arl3) GTPase
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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