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lin7a lin-7 homolog A (C. elegans) [ Danio rerio (zebrafish) ]

Gene ID: 393682, updated on 4-Jan-2025

Summary

Official Symbol
lin7aprovided by ZNC
Official Full Name
lin-7 homolog A (C. elegans)provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1665
See related
Ensembl:ENSDARG00000013414 AllianceGenome:ZFIN:ZDB-GENE-040426-1665
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
lin7b; zgc:73090
Summary
Predicted to be involved in exocytosis and protein transport. Predicted to be located in bicellular tight junction and plasma membrane. Is expressed in myotome and nervous system. Orthologous to human LIN7A (lin-7 homolog A, crumbs cell polarity complex component). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See lin7a in Genome Data Viewer
Location:
chromosome: 4
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (21752320..21851473, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (22030787..22130520, complement)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene myogenic factor 6 Neighboring gene microRNA mir-3906 Neighboring gene myogenic factor 5 Neighboring gene acyl-CoA synthetase short chain family member 3 Neighboring gene PTPRF interacting protein alpha 2 Neighboring gene uncharacterized LOC137491548 Neighboring gene LLP homolog, long-term synaptic facilitation factor

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC73090

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within exocytosis IEA
Inferred from Electronic Annotation
more info
 
involved_in exocytosis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
 
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein lin-7 homolog A
Names
neuroepithelial polarity protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200709.1NP_957003.1  protein lin-7 homolog A

    See identical proteins and their annotated locations for NP_957003.1

    Status: PROVISIONAL

    Source sequence(s)
    BC059460
    UniProtKB/TrEMBL
    Q2M5E8, Q5TZ23, Q6PC63
    Related
    ENSDARP00000022617.8, ENSDART00000019748.9
    Conserved Domains (2) summary
    smart00569
    Location:1669
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:92173
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    21752320..21851473 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005164866.5XP_005164923.1  protein lin-7 homolog A isoform X1

    UniProtKB/TrEMBL
    A0A8M2BC73
    Conserved Domains (2) summary
    smart00569
    Location:1669
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:92173
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...