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ghitm growth hormone inducible transmembrane protein [ Danio rerio (zebrafish) ]

Gene ID: 393563, updated on 4-Jan-2025

Summary

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Official Symbol
ghitmprovided by ZNC
Official Full Name
growth hormone inducible transmembrane proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1537
See related
AllianceGenome:ZFIN:ZDB-GENE-040426-1537
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:66108; zgc:77363; unm_sa8494
Summary
Predicted to enable calcium channel activity. Predicted to be involved in calcium export from the mitochondrion and inner mitochondrial membrane organization. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Orthologous to human GHITM (growth hormone inducible transmembrane protein). [provided by Alliance of Genome Resources, Jan 2025]
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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See ghitm in Genome Data Viewer
Location:
chromosome: 12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (49000313..49033186, complement)
RS_2024_08 current GRCz11 (GCF_000002035.6) Unplaced Scaffold NW_003335146.1 (1..677, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (48978784..49011657, complement)
105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003335146.1 (1..677, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene calcium-activated potassium channel subunit alpha-1-like Neighboring gene cadherin-related family member 1a Neighboring gene leucine-rich repeat, immunoglobulin-like and transmembrane domains 1b Neighboring gene carbohydrate (chondroitin 6) sulfotransferase 3b Neighboring gene uncharacterized LOC108191766 Neighboring gene protein mago nashi homolog Neighboring gene zinc finger protein 503 Neighboring gene uncharacterized LOC137496861

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC66108

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in calcium export from the mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in inner mitochondrial membrane organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
growth hormone-inducible transmembrane protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200591.1 → NP_956885.1  growth hormone-inducible transmembrane protein

    See identical proteins and their annotated locations for NP_956885.1

    Status: PROVISIONAL

    Source sequence(s)
    BC056745
    UniProtKB/TrEMBL
    Q6NYV2
    Conserved Domains (1) summary
    cd10431
    Location:93 → 340
    GHITM; Growth-hormone inducible transmembrane protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    49000313..49033186 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 Primary Assembly

Genomic

  1. NW_003335146.1 Reference GRCz11 Primary Assembly

    Range
    1..677 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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