U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

trip13 thyroid hormone receptor interactor 13 [ Danio rerio (zebrafish) ]

Gene ID: 393554, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
trip13provided by ZNC
Official Full Name
thyroid hormone receptor interactor 13provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1488
See related
Ensembl:ENSDARG00000025043 AllianceGenome:ZFIN:ZDB-GENE-040426-1488
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:65952; im:6901078
Summary
Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in several processes, including double-strand break repair; meiosis I; and meiotic recombination checkpoint signaling. Predicted to act upstream of or within cell differentiation and meiotic cell cycle. Predicted to be active in chromosome and nucleus. Human ortholog(s) of this gene implicated in mosaic variegated aneuploidy syndrome 3. Orthologous to human TRIP13 (thyroid hormone receptor interactor 13). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See trip13 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (52966843..52991485)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (53079057..53103713)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type containing 11 Neighboring gene bromodomain containing 9 Neighboring gene NKD inhibitor of WNT signaling pathway 2b Neighboring gene zgc:158766 Neighboring gene uncharacterized LOC101885705

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Distinct Molecular Signature of Murine Fetal Liver and Adult Hematopoietic Stem Cells Identify Novel Regulators of Hematopoietic Stem Cell Function. Manesia JK, et al. Stem Cells Dev, 2017 Apr 15. PMID 27958775, Free PMC Article
  2. Dhx38 is required for the maintenance and differentiation of erythro-myeloid progenitors and hematopoietic stem cells by alternative splicing. Tu J, et al. Development, 2022 Sep 1. PMID 35929537
  3. Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression. Bertrand S, et al. PLoS Genet, 2007 Nov. PMID 17997606, Free PMC Article
  4. Many genes in fish have species-specific asymmetric rates of molecular evolution. Steinke D, et al. BMC Genomics, 2006 Feb 8. PMID 16466575, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC65952

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in anatomical structure morphogenesis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in double-strand break repair ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in meiotic recombination checkpoint signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within oogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in oogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in reciprocal meiotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in reciprocal meiotic recombination IEA
Inferred from Electronic Annotation
more info
  
involved_in reciprocal meiotic recombination ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within spermatogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in spermatogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in synaptonemal complex assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in chromosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
pachytene checkpoint protein 2 homolog
Names
TR-interacting protein 13 homolog
TRIP-13 homolog
thyroid hormone receptor interactor 13 homolog
thyroid receptor-interacting protein 13 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200582.1 → NP_956876.1  pachytene checkpoint protein 2 homolog

    See identical proteins and their annotated locations for NP_956876.1

    Status: PROVISIONAL

    Source sequence(s)
    BC056713
    UniProtKB/Swiss-Prot
    Q6PH52
    Related
    ENSDARP00000049098.5, ENSDART00000049099.7
    Conserved Domains (2) summary
    smart00382
    Location:164 → 314
    AAA; ATPases associated with a variety of cellular activities
    pfam00004
    Location:167 → 312
    AAA; ATPase family associated with various cellular activities (AAA)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    52966843..52991485
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005170125.5 → XP_005170182.1  pachytene checkpoint protein 2 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8M2BHH9, F1RBS4
    Conserved Domains (2) summary
    smart00382
    Location:164 → 314
    AAA; ATPases associated with a variety of cellular activities
    pfam00004
    Location:167 → 312
    AAA; ATPase family associated with various cellular activities (AAA)

  2. XM_017351326.3 → XP_017206815.1  pachytene checkpoint protein 2 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8M2BHH9, F1RBS4
    Conserved Domains (2) summary
    smart00382
    Location:164 → 314
    AAA; ATPases associated with a variety of cellular activities
    pfam00004
    Location:167 → 312
    AAA; ATPase family associated with various cellular activities (AAA)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PH52.1 GenPept UniProtKB/Swiss-Prot:Q6PH52

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools