psmd2 proteasome 26S subunit ubiquitin receptor, non-ATPase 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: psmd2provided by ZNC
Official Full Name: proteasome 26S subunit ubiquitin receptor, non-ATPase 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1480
See related: Ensembl:ENSDARG00000099653 Ensembl:ENSDARG00000103190 AllianceGenome:ZFIN:ZDB-GENE-040426-1480
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:65921
Summary: Predicted to enable enzyme regulator activity. Acts upstream of or within retina development in camera-type eye. Predicted to be part of proteasome regulatory particle, base subcomplex. Is expressed in eye and neural tube. Orthologous to human PSMD2 (proteasome 26S subunit ubiquitin receptor, non-ATPase 2). [provided by Alliance of Genome Resources, Dec 2024]
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Un

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	Unplaced Scaffold	NW_003335383.2 (2139..15842, complement)
RS_2024_08	current	GRCz11 (GCF_000002035.6)	Unplaced Scaffold	NW_003335384.1 (923..21898, complement)
RS_2024_08	current	GRCz11 (GCF_000002035.6)	Unplaced Scaffold	NW_003335386.2 (76722..77239, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	Unplaced Scaffold	NW_003335383.2 (2139..15842, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	Unplaced Scaffold	NW_003335384.1 (923..21898, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	Unplaced Scaffold	NW_003335386.2 (76722..77239, complement)

NW_003335384.1 Genomic Context describing neighboring genes

NW_003335386.2 Genomic Context describing neighboring genes

NW_003335383.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables enzyme regulator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of protein catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within retina development in camera-type eye	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome complex	IEA Inferred from Electronic Annotation more info
part_of proteasome regulatory particle, base subcomplex	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome regulatory particle, base subcomplex	IEA Inferred from Electronic Annotation more info
is_active_in proteasome storage granule	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 26S proteasome non-ATPase regulatory subunit 2

Names: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2; proteasome 26S subunit, non-ATPase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200546.1 → NP_956840.1 26S proteasome non-ATPase regulatory subunit 2

See identical proteins and their annotated locations for NP_956840.1

Status: PROVISIONAL

Source sequence(s)

BC056516

UniProtKB/TrEMBL

Q6PHK7

Related

ENSDARP00000131682.2, ENSDARP00000134127.2, ENSDART00000163880.2, ENSDART00000164577.2

Conserved Domains (3) summary

COG5110
Location:2 → 895

RPN1; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]

pfam01851
Location:470 → 504

PC_rep; Proteasome/cyclosome repeat

pfam11861
Location:2 → 72

DUF3381; Domain of unknown function (DUF3381)