tm9sf4 transmembrane 9 superfamily protein member 4 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tm9sf4provided by ZNC
Official Full Name: transmembrane 9 superfamily protein member 4provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1575
See related: Ensembl:ENSDARG00000002536 AllianceGenome:ZFIN:ZDB-GENE-040426-1575
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:66234
Summary: Predicted to be involved in protein localization to membrane. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Predicted to be active in membrane. Is expressed in several structures, including digestive system; eye; heart; integument; and pleuroperitoneal region. Orthologous to human TM9SF4 (transmembrane 9 superfamily member 4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (7548908..7578890)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (7614936..7644918)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A conserved immunoreceptor tyrosine-based inhibition motif exists in the cytoplasmic domain between transmembrane domains 7 & 8 & at the C-terminal end in TM9SF4. A conserved TRAF2 binding domain is predicted in the cytoplasmic regions of TM9SF4.
Title: Comparative analysis of nonaspanin protein sequences and expression studies in zebrafish.

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in intracellular monoatomic cation homeostasis	IEA Inferred from Electronic Annotation more info
involved_in protein localization to membrane	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in intracellular membrane-bounded organelle	IEA Inferred from Electronic Annotation more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: transmembrane 9 superfamily member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200510.2 → NP_956804.2 transmembrane 9 superfamily member 4 precursor

Status: VALIDATED

Source sequence(s)

CU633736, EH432370, EH475566, EH486879

UniProtKB/TrEMBL

A0A8M1PCY3, F1Q4U1

Related

ENSDARP00000013759.7, ENSDART00000006765.9

Conserved Domains (1) summary

pfam02990
Location:59 → 608

EMP70; Endomembrane protein 70