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ascc2 activating signal cointegrator 1 complex subunit 2 [ Danio rerio (zebrafish) ]

Gene ID: 393414, updated on 9-Dec-2024

Summary

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Official Symbol
ascc2provided by ZNC
Official Full Name
activating signal cointegrator 1 complex subunit 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1223
See related
Ensembl:ENSDARG00000013058 AllianceGenome:ZFIN:ZDB-GENE-040426-1223
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:63666
Summary
Predicted to enable ubiquitin binding activity. Predicted to be involved in regulation of DNA-templated transcription. Orthologous to human ASCC2 (activating signal cointegrator 1 complex subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See ascc2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (18012140..18035585)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (17508155..17531584)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene si:dkey-112e17.1 Neighboring gene uncharacterized LOC137495574 Neighboring gene zinc finger DHHC-type palmitoyltransferase 8b Neighboring gene uncharacterized LOC110439809 Neighboring gene ring finger protein 215 Neighboring gene histone cell cycle regulator a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Transcriptional response of zebrafish larvae exposed to lindane reveals two detoxification genes of ABC transporter family (abcg5 and abcg8). Zhang L, et al. Comp Biochem Physiol C Toxicol Pharmacol, 2020 Jun. PMID 32244031
  2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC63666

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
activating signal cointegrator 1 complex subunit 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200442.1 → NP_956736.1  activating signal cointegrator 1 complex subunit 2

    See identical proteins and their annotated locations for NP_956736.1

    Status: PROVISIONAL

    Source sequence(s)
    BC054929
    UniProtKB/TrEMBL
    Q7SYC1
    Related
    ENSDARP00000048858.4, ENSDART00000048859.6
    Conserved Domains (1) summary
    cd14364
    Location:479 → 518
    CUE_ASCC2; CUE domain found in activating signal cointegrator 1 complex subunit 2 (ASCC2) and similar proteins

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    18012140..18035585
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005165069.5 → XP_005165126.1  activating signal cointegrator 1 complex subunit 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BC77, A2CEX4
    Conserved Domains (1) summary
    cd14364
    Location:479 → 518
    CUE_ASCC2; CUE domain found in activating signal cointegrator 1 complex subunit 2 (ASCC2) and similar proteins
Nucleotide Protein Strain
Heading Accession and Version

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