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taf8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor [ Danio rerio (zebrafish) ]

Gene ID: 393256, updated on 9-Dec-2024

Summary

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Official Symbol
taf8provided by ZNC
Official Full Name
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1013
See related
Ensembl:ENSDARG00000026806 AllianceGenome:ZFIN:ZDB-GENE-040426-1013
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
tbnl; zgc:56401; zgc:77837
Summary
Predicted to enable protein heterodimerization activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to act upstream of or within cell differentiation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription factor TFIID complex. Orthologous to human TAF8 (TATA-box binding protein associated factor 8). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See taf8 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (32392461..32401225)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (32465919..32474461)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 39 member 5 Neighboring gene ankyrin repeat domain 52a Neighboring gene si:ch211-66i15.4 Neighboring gene si:ch211-66i15.5 Neighboring gene transcription initiation factor TFIID subunit 8-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters. Burket CT, et al. Transgenic Res, 2008 Apr. PMID 17968670, Free PMC Article
  2. Identification of 315 genes essential for early zebrafish development. Amsterdam A, et al. Proc Natl Acad Sci U S A, 2004 Aug 31. PMID 15256591, Free PMC Article
  3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC56401

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in transcription initiation at RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIID complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIID complex IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIID complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
transcription initiation factor TFIID subunit 8
Names
TBP-associated factor 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200286.1 → NP_956580.1  transcription initiation factor TFIID subunit 8

    See identical proteins and their annotated locations for NP_956580.1

    Status: PROVISIONAL

    Source sequence(s)
    BC049422
    UniProtKB/Swiss-Prot
    Q6P0T2
    Related
    ENSDARP00000130755.2, ENSDART00000171715.2
    Conserved Domains (2) summary
    cd08049
    Location:146 → 199
    TAF8; TATA Binding Protein (TBP) Associated Factor 8
    pfam07524
    Location:32 → 108
    Bromo_TP; Bromodomain associated

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    32392461..32401225
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005162303.5 → XP_005162360.1  transcription initiation factor TFIID subunit 8 isoform X1

    See identical proteins and their annotated locations for XP_005162360.1

    UniProtKB/Swiss-Prot
    Q6P0T2, Q7ZWG5
    Related
    ENSDARP00000032165.8, ENSDART00000039498.10
    Conserved Domains (2) summary
    cd08049
    Location:146 → 199
    TAF8; TATA Binding Protein (TBP) Associated Factor 8
    pfam07524
    Location:32 → 108
    Bromo_TP; Bromodomain associated

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395161.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    358393..366843
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P0T2.1 GenPept UniProtKB/Swiss-Prot:Q6P0T2

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