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loaf lost and found [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39325, updated on 4-Jan-2025

Summary

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Official Symbol
loafprovided by FlyBase
Official Full Name
lost and foundprovided by FlyBase
Primary source
FLYBASE:FBgn0036202
Locus tag
Dmel_CG6024
See related
AllianceGenome:FB:FBgn0036202
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6024; CT18912; Dmel\CG6024
Summary
Located in cytoplasm. Is expressed in adult head; embryonic brain; larval nervous system; larval ventral nerve cord; and organism. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See loaf in Genome Data Viewer
Location:
68D3-68D4; 3-36 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11733589..11766182, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11726689..11759282, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene bmcp Neighboring gene sisters unbound Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 68a Neighboring gene Mucin 68D Neighboring gene mir-314 stem loop

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. R7 photoreceptor axon targeting depends on the relative levels of lost and found expression in R7 and its synaptic partners. Douthit J, et al. Elife, 2021 May 18. PMID 34003117, Free PMC Article
  2. Differential activation of JAK-STAT signaling reveals functional compartmentalization in Drosophila blood progenitors. Rodrigues D, et al. Elife, 2021 Feb 17. PMID 33594977, Free PMC Article
  3. RNA polymerase II kinetics in polo polyadenylation signal selection. Pinto PA, et al. EMBO J, 2011 May 20. PMID 21602789, Free PMC Article
  4. A Cyclin E Centered Genetic Network Contributes to Alcohol-Induced Variation in Drosophila Development. Morozova TV, et al. G3 (Bethesda), 2018 Jul 31. PMID 29871898, Free PMC Article
  5. Systematic identification of genes regulating synaptic remodeling in the Drosophila visual system. Araki T, et al. Genes Genet Syst, 2020 Aug 27. PMID 32493879

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
acts_upstream_of synaptic target recognition IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
lost and found
Names
CG6024-PC
CG6024-PF
CG6024-PG
loaf-PC
loaf-PF
loaf-PG

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    11733589..11766182 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001104119.2 → NP_001097589.2  lost and found, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097589.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BIG2
    Conserved Domains (2) summary
    smart00192
    Location:216 → 247
    LDLa; Low-density lipoprotein receptor domain class A
    cl00049
    Location:121 → 209
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

  2. NM_001382185.1 → NP_001368949.1  lost and found, isoform G [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6J3SW69
    Conserved Domains (1) summary
    smart00192
    Location:216 → 247
    LDLa; Low-density lipoprotein receptor domain class A

  3. NM_001104117.2 → NP_001097587.1  lost and found, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097587.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BIG2
    Conserved Domains (2) summary
    smart00192
    Location:216 → 247
    LDLa; Low-density lipoprotein receptor domain class A
    cl00049
    Location:121 → 209
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A6J3SW69 A0A6J3SW69
Q5BIG2 Q5BIG2

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