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rasl11b RAS-like, family 11, member B [ Danio rerio (zebrafish) ]

Gene ID: 393109, updated on 4-Jan-2025

Summary

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Official Symbol
rasl11bprovided by ZNC
Official Full Name
RAS-like, family 11, member Bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-793
See related
Ensembl:ENSDARG00000015611 AllianceGenome:ZFIN:ZDB-GENE-040426-793
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc21f04; zgc:55750; zgc:77749; wu:fc21f04
Summary
Predicted to enable G protein activity and GTP binding activity. Acts upstream of or within mesendoderm development. Is expressed in several structures, including axis; central nervous system; presumptive ectoderm; shield; and tail bud. Orthologous to human RASL11B (RAS like family 11 member B). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See rasl11b in Genome Data Viewer
Location:
chromosome: 20
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (23022985..23026223, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (23123885..23127123, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene FIP1 like 1a (S. cerevisiae) Neighboring gene sec1 family domain containing 2 Neighboring gene uncharacterized LOC137488644 Neighboring gene uncharacterized LOC108180337 Neighboring gene uncharacterized LOC100536039 Neighboring gene small nucleolar RNA SNORA26

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Rasl11b knock down in zebrafish suppresses one-eyed-pinhead mutant phenotype. Pézeron G, et al. PLoS One, 2008 Jan 16. PMID 18197245, Free PMC Article
  2. RASL11A, member of a novel small monomeric GTPase gene family, is down-regulated in prostate tumors. Louro R, et al. Biochem Biophys Res Commun, 2004 Apr 9. PMID 15033445
  3. Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation. Taylor AM, et al. Exp Hematol, 2012 Mar. PMID 22120640, Free PMC Article
  4. Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components. van der Sar AM, et al. Mol Immunol, 2009 Jul. PMID 19409617
  5. Full transcriptome analysis of early dorsoventral patterning in zebrafish. Fodor E, et al. PLoS One, 2013. PMID 23922899, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC55750

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G protein activity IEA
Inferred from Electronic Annotation
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within mesendoderm development IGI
Inferred from Genetic Interaction
more info
 PubMed 

General protein information

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Preferred Names
ras-like protein family member 11B
NP_956434.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200140.1 → NP_956434.1  ras-like protein family member 11B

    See identical proteins and their annotated locations for NP_956434.1

    Status: PROVISIONAL

    Source sequence(s)
    BC044471
    UniProtKB/Swiss-Prot
    Q001T7, Q6P0U3, Q803I5
    Related
    ENSDARP00000003188.6, ENSDART00000015755.8
    Conserved Domains (2) summary
    smart00010
    Location:22 → 187
    small_GTPase; Small GTPase of the Ras superfamily; ill-defined subfamily
    cd04146
    Location:25 → 193
    RERG_RasL11_like; Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    23022985..23026223 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P0U3.1 GenPept UniProtKB/Swiss-Prot:Q6P0U3

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