Cyp40 - Cyclophilin 40
Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in RISC complex assembly; piRNA processing; and piRNA-mediated gene silencing by mRNA destabilization. Acts upstream of with a positive effect on spermatogenesis. Part of protein folding chaperone complex. Is active in cytosol. Is expressed in adult head; organism; spermatogonium; and testis. Orthologous to human PPID (peptidylprolyl isomerase D). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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