OR56B2 olfactory receptor family 56 subfamily B member 2 [Homo sapiens (human)] - Gene

Summary

Official Symbol: OR56B2provided by HGNC
Official Full Name: olfactory receptor family 56 subfamily B member 2provided by HGNC
Primary source: HGNC:HGNC:15246
See related: Ensembl:ENSG00000181017 AllianceGenome:HGNC:15246
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: OR11-63; OR56B2P
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Orthologs: all
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Genomic context

Location:: 11p15.4

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	11	NC_000011.10 (5761153..5769080)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	11	NC_060935.1 (5818966..5826891)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	11	NC_000011.9 (5782383..5790310)

Chromosome 11 - NC_000011.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

REN99533 (e-PCR)
- UniSTS:424330

REN99534 (e-PCR)
- UniSTS:424331

REN99535 (e-PCR)
- UniSTS:424332

REN99536 (e-PCR)
- UniSTS:424333

REN99537 (e-PCR)
- UniSTS:424334

REN99538 (e-PCR)
- UniSTS:424335

REN99539 (e-PCR)
- UniSTS:424336

REN99540 (e-PCR)
- UniSTS:424337

REN99541 (e-PCR)
- UniSTS:424338

REN99542 (e-PCR)
- UniSTS:424339

REN99543 (e-PCR)
- UniSTS:424340

REN99544 (e-PCR)
- UniSTS:424341

REN99545 (e-PCR)
- UniSTS:424342

REN99546 (e-PCR)
- UniSTS:424343

REN99547 (e-PCR)
- UniSTS:424344

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in detection of chemical stimulus involved in sensory perception of smell	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative olfactory receptor 56B2

Names: Olfactory receptor 56B2; olfactory receptor OR11-63; olfactory receptor family 56 subfamily B member 2 pseudogene; seven transmembrane helix receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001396057.1 → NP_001382986.1 putative olfactory receptor 56B2

Status: VALIDATED

Source sequence(s)

AC131574

Consensus CDS

CCDS91426.1

UniProtKB/Swiss-Prot

Q8NGI1

UniProtKB/TrEMBL

A0A6Q8PH80

Related

ENSP00000502530.1, ENST00000641377.2

Conserved Domains (1) summary

cd15223
Location:58 → 309

7tmA_OR56-like; olfactory receptor family 56 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors