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Fhos - Formin homology 2 domain containing

Predicted to enable actin filament binding activity. Involved in several processes, including instar larval or pupal morphogenesis; muscle cell cellular homeostasis; and positive regulation of stress fiber assembly. Located in nucleus and perinuclear region of cytoplasm. Is expressed in several structures, including adult heart; embryonic/larval dorsal vessel; gland; imaginal disc; and region of integument. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy. Orthologous to several human genes including FHOD3 (formin homology 2 domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa