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PAGE2B PAGE family member 2B [ Homo sapiens (human) ]

Gene ID: 389860, updated on 27-Nov-2024

Summary

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Official Symbol
PAGE2Bprovided by HGNC
Official Full Name
PAGE family member 2Bprovided by HGNC
Primary source
HGNC:HGNC:31805
See related
Ensembl:ENSG00000238269 AllianceGenome:HGNC:31805
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT16.5; GAGEE3; PAGE-2B
Expression
Restricted expression toward testis (RPKM 8.7) See more
Orthologs
all
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Genomic context

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See PAGE2B in Genome Data Viewer
Location:
Xp11.21
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (55028117..55078909)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (54321243..54372032)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (55101463..55105342)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene ReSE screen-validated silencer GRCh37_chrX:54962395-54962556 Neighboring gene 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:54977103-54977603 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20865 Neighboring gene Sharpr-MPRA regulatory regions 2439 and 5762 Neighboring gene ALAS2 intronic erythroid enhancer Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene ALAS2 intron 1 and 3 erythroid regulatory elements Neighboring gene 5'-aminolevulinate synthase 2 Neighboring gene HDGFL3 pseudogene 1 Neighboring gene PAGE family member 2 Neighboring gene CRISPRi-validated cis-regulatory element chrX.1184 Neighboring gene component of oligomeric golgi complex 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability. Achuthankutty D, et al. J Cell Biol, 2019 Dec 2. PMID 31615875, Free PMC Article
  2. The DNA sequence of the human X chromosome. Ross MT, et al. Nature, 2005 Mar 17. PMID 15772651, Free PMC Article
  3. Transcriptome analysis of human gastric cancer. Oh JH, et al. Mamm Genome, 2005 Dec. PMID 16341674
  4. Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. Huttlin EL, et al. Cell, 2021 May 27. PMID 33961781, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

General protein information

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Preferred Names
putative G antigen family E member 3
Names
G antigen, family E, 3
P antigen family, member 2B
prostate-associated gene 2B protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001015038.3 → NP_001015038.1  putative G antigen family E member 3

    See identical proteins and their annotated locations for NP_001015038.1

    Status: VALIDATED

    Source sequence(s)
    AL590240, BM782405, HY192793
    Consensus CDS
    CCDS35304.1
    UniProtKB/Swiss-Prot
    A1L414, Q5JRK9
    UniProtKB/TrEMBL
    Q5JRL0
    Related
    ENSP00000364110.1, ENST00000374971.2
    Conserved Domains (1) summary
    pfam05831
    Location:1 → 107
    GAGE; GAGE protein

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    55028117..55078909
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011530785.3 → XP_011529087.1  putative G antigen family E member 3 isoform X1

    See identical proteins and their annotated locations for XP_011529087.1

    Conserved Domains (1) summary
    pfam05831
    Location:24 → 133
    GAGE; GAGE protein

  2. XM_011530786.4 → XP_011529088.1  putative G antigen family E member 3 isoform X2

    See identical proteins and their annotated locations for XP_011529088.1

    UniProtKB/TrEMBL
    Q5JRL0
    Conserved Domains (1) summary
    pfam05831
    Location:6 → 115
    GAGE; GAGE protein

  3. XM_017029513.2 → XP_016885002.1  putative G antigen family E member 3 isoform X3

    UniProtKB/Swiss-Prot
    A1L414, Q5JRK9
    UniProtKB/TrEMBL
    Q5JRL0
    Conserved Domains (1) summary
    pfam05831
    Location:1 → 107
    GAGE; GAGE protein

  4. XM_011530787.3 → XP_011529089.1  putative G antigen family E member 3 isoform X3

    See identical proteins and their annotated locations for XP_011529089.1

    UniProtKB/Swiss-Prot
    A1L414, Q5JRK9
    UniProtKB/TrEMBL
    Q5JRL0
    Conserved Domains (1) summary
    pfam05831
    Location:1 → 107
    GAGE; GAGE protein

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    54321243..54372032
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054327042.1 → XP_054183017.1  putative G antigen family E member 3 isoform X1

  2. XM_054327043.1 → XP_054183018.1  putative G antigen family E member 3 isoform X2

  3. XM_054327044.1 → XP_054183019.1  putative G antigen family E member 3 isoform X3

    UniProtKB/Swiss-Prot
    A1L414, Q5JRK9

  4. XM_054327045.1 → XP_054183020.1  putative G antigen family E member 3 isoform X3

    UniProtKB/Swiss-Prot
    A1L414, Q5JRK9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5JRK9.1 GenPept UniProtKB/Swiss-Prot:Q5JRK9

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