U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

RpL14 Ribosomal protein L14 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38983, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
RpL14provided by FlyBase
Official Full Name
Ribosomal protein L14provided by FlyBase
Primary source
FLYBASE:FBgn0017579
Locus tag
Dmel_CG6253
See related
AllianceGenome:FB:FBgn0017579
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:Posey193U; anon-EST:Posey6; CG6253; Dmel\CG6253; L14; L14e; M(3); M(3)66; M(3)66D; M66D; Rp L14; rpl14; RPL14
Summary
A structural constituent of ribosome. Involved in negative regulation of neuron apoptotic process. Located in cytosolic ribosome. Is expressed in adult head and adult heart. Used to study congenital heart disease. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Orthologous to human RPL14 (ribosomal protein L14). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See RpL14 in Genome Data Viewer
Location:
66D8-66D8; 3-26 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8601006..8602392)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8594106..8595492)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene rhea Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Negative elongation factor E Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. First steps towards underdominant genetic transformation of insect populations. Reeves RG, et al. PLoS One, 2014. PMID 24844466, Free PMC Article
  2. Primary structure of Drosophila ribosomal protein L14 and identification of conserved protein motifs. Haynes SR. DNA Seq, 1997. PMID 9522130
  3. Silencing the Drosophila ribosomal protein L14 gene using targeted RNA interference causes distinct somatic anomalies. Enerly E, et al. Gene, 2003 Nov 27. PMID 14597387
  4. The Drosophila ribosomal protein L14-encoding gene, identified by a novel Minute mutation in a dense cluster of previously undescribed genes in cytogenetic region 66D. Saebøe-Larssen S, et al. Mol Gen Genet, 1997 Jun. PMID 9236770
  5. Drosophila S6 kinase: a regulator of cell size. Montagne J, et al. Science, 1999 Sep 24. PMID 10497130

See all (83) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome HDA PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in cytoplasmic translation TAS
Traceable Author Statement
more info
 PubMed 
involved_in negative regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 
located_in cytosolic ribosome HDA PubMed 
located_in cytosolic ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ribosomal protein L14
Names
60 S ribosomal protein L14
CG6253-PA
Minute(3)66D
RpL14-PA
minute (3)66D

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    8601006..8602392
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079251.4 → NP_523975.1  ribosomal protein L14 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523975.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P55841, Q9VSM3
    UniProtKB/TrEMBL
    A0A1B2AIV7, Q5U0W4
    Related
    FBpp0076359
    Conserved Domains (2) summary
    cd06088
    Location:7 → 81
    KOW_RPL14; KOW motif of Ribosomal Protein L14
    pfam01929
    Location:46 → 120
    Ribosomal_L14e; Ribosomal protein L14
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P55841.1 P55841
Q5BIL1 Q5BIL1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous