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Pop4 POP4 ribonuclease P/MRP subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38889, updated on 9-Dec-2024

Summary

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Official Symbol
Pop4provided by FlyBase
Official Full Name
POP4 ribonuclease P/MRP subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0035831
Locus tag
Dmel_CG8038
See related
AllianceGenome:FB:FBgn0035831
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0172774.38; BcDNA:LD45688; CG8038; Dmel\CG8038; Rpp29
Summary
Predicted to enable rRNA primary transcript binding activity and ribonuclease P RNA binding activity. Predicted to be involved in rRNA processing and tRNA 5'-leader removal. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Orthologous to human POP4 (POP4 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Pop4 in Genome Data Viewer
Location:
66A21-66A22; 3-21 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7977805..7978650, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7970905..7971750, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Ribonuclease X25 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Heterochromatin protein 4 Neighboring gene nemo Neighboring gene transfer RNA:Alanine-AGC 2-1 Neighboring gene antisense RNA:CR45867 Neighboring gene bip1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Biogenesis of RNase P RNA from an intron requires co-assembly with cognate protein subunits. Palsule G, et al. Nucleic Acids Res, 2019 Sep 19. PMID 31287870, Free PMC Article
  2. Inventory and analysis of the protein subunits of the ribonucleases P and MRP provides further evidence of homology between the yeast and human enzymes. Rosenblad MA, et al. Nucleic Acids Res, 2006. PMID 16998185, Free PMC Article
  3. Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells. Mohr SE, et al. G3 (Bethesda), 2015 Jul 21. PMID 26199285, Free PMC Article
  4. Transcriptional response to dietary restriction in Drosophila melanogaster. Ding F, et al. J Insect Physiol, 2014 Oct. PMID 24819200, Free PMC Article
  5. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables rRNA primary transcript binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables ribonuclease P RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribonuclease P RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables ribonuclease P RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA processing ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in tRNA 5'-leader removal IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA 5'-leader removal ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in tRNA processing ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of multimeric ribonuclease P complex ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of nucleolar ribonuclease P complex ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of ribonuclease MRP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonuclease MRP complex IEA
Inferred from Electronic Annotation
more info
  
part_of ribonuclease MRP complex ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of ribonuclease P complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonuclease P complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
POP4 ribonuclease P/MRP subunit
Names
CG8038-PA
Pop4-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    7977805..7978650 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139911.3 → NP_648168.1  POP4 ribonuclease P/MRP subunit [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648168.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C4XVM6, Q9VSC6
    Related
    FBpp0076478
    Conserved Domains (1) summary
    smart00538
    Location:111 → 201
    POP4; A domain found in a protein subunit of human RNase MRP and RNase P ribonucleoprotein complexes and archaeal proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MSA7 Q8MSA7
Q9VSC6 Q9VSC6

Gene LinkOut

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