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dpr13 defective proboscis extension response 13 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3885598, updated on 9-Dec-2024

Summary

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Official Symbol
dpr13provided by FlyBase
Official Full Name
defective proboscis extension response 13provided by FlyBase
Primary source
FLYBASE:FBgn0034286
Locus tag
Dmel_CG33996
See related
AllianceGenome:FB:FBgn0034286
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG12557; CG14493; CG33996; CT34204; Dmel\CG33996; Dm_2R:58906; Dpr-13; Dpr13
Summary
Involved in synapse organization. Predicted to be located in plasma membrane. Predicted to be active in neuron projection membrane. Is expressed in dorsal sensory complex proper primordium; embryonic brain; larval ventral nerve cord; and ventral sensory complex primordium. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See dpr13 in Genome Data Viewer
Location:
55A3-55A3; 2-84 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17975122..18007902, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13862627..13895407, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44418 Neighboring gene Protein phosphatase Y at 55A Neighboring gene long non-coding RNA:CR44419 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila. Barish S, et al. PLoS Genet, 2018 Aug. PMID 30102700, Free PMC Article
  2. Defective proboscis extension response (DPR), a member of the Ig superfamily required for the gustatory response to salt. Nakamura M, et al. J Neurosci, 2002 May 1. PMID 11978823, Free PMC Article
  3. Neural immunoglobulin superfamily interaction networks. Zinn K, et al. Curr Opin Neurobiol, 2017 Aug. PMID 28558267, Free PMC Article
  4. Population Genomics of sub-saharan Drosophila melanogaster: African diversity and non-African admixture. Pool JE, et al. PLoS Genet, 2012. PMID 23284287, Free PMC Article
  5. Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons. Wang Y, et al. Development, 2022 May 15. PMID 35502740, Free PMC Article

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in sensory perception of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in synapse organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in synapse organization IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
is_active_in neuron projection membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
defective proboscis extension response 13
Names
CG33996-PB
CG33996-PC
dpr13-PB
dpr13-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17975122..18007902 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001038867.4 → NP_001033956.2  defective proboscis extension response 13, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033956.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZB15, C5WLT5, C6TP32
    Conserved Domains (3) summary
    smart00408
    Location:292 → 361
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:285 → 362
    IG_like; Immunoglobulin like
    pfam07686
    Location:180 → 276
    V-set; Immunoglobulin V-set domain

  2. NM_001299626.1 → NP_001286555.1  defective proboscis extension response 13, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286555.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4LFL9, C5WLT5
    Conserved Domains (3) summary
    smart00408
    Location:291 → 360
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:284 → 361
    IG_like; Immunoglobulin like
    pfam07686
    Location:180 → 276
    V-set; Immunoglobulin V-set domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LFL9 A0A0B4LFL9
A1ZB15 A1ZB15

Gene LinkOut

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