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Dpm3 Dolichyl-phosphate mannosyltransferase subunit 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3885575, updated on 9-Dec-2024

Summary

Official Symbol
Dpm3provided by FlyBase
Official Full Name
Dolichyl-phosphate mannosyltransferase subunit 3provided by FlyBase
Primary source
FLYBASE:FBgn0053977
Locus tag
Dmel_CG33977
See related
AllianceGenome:FB:FBgn0053977
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG33977; Dmel\CG33977; DPM3
Summary
Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be part of dolichol-phosphate-mannose synthase complex. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type I and muscular dystrophy-dystroglycanopathy type B15. Orthologous to human DPM3 (dolichyl-phosphate mannosyltransferase subunit 3, regulatory). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Dpm3 in Genome Data Viewer
Location:
87E9-87E10; 3-53 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (13402559..13403051, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9228281..9228773, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Gamma-interferon-inducible lysosomal thiol reductase 1 Neighboring gene yellow-e3 Neighboring gene yellow-e2

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in GPI anchor biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of dolichol-phosphate-mannose synthase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Dolichyl-phosphate mannosyltransferase subunit 3
Names
CG33977-PA
Dpm3-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    13402559..13403051 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001038962.3NP_001034051.1  Dolichyl-phosphate mannosyltransferase subunit 3 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001034051.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3DMY4, Q2PDR0
    Conserved Domains (1) summary
    pfam08285
    Location:791
    DPM3; Dolichol-phosphate mannosyltransferase subunit 3 (DPM3)