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mrva minerva [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38808, updated on 9-Dec-2024

Summary

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Official Symbol
mrvaprovided by FlyBase
Official Full Name
minervaprovided by FlyBase
Primary source
FLYBASE:FBgn0035763
Locus tag
Dmel_CG8602
See related
AllianceGenome:FB:FBgn0035763
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0118547.349; anon-WO0118547.382; CG8602; Dmel\CG8602
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Is active in Golgi membrane and endosome. Is expressed in several structures, including adult head; adult heart; amnioserosa; plasmatocyte primordium; and yolk nucleus. Orthologous to human MFSD1 (major facilitator superfamily domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See mrva in Genome Data Viewer
Location:
65F4-65F4; 3-20 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7326273..7328842, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7319373..7321942, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Rho guanine nucleotide exchange factor 4 Neighboring gene RAD50 interactor 1 Neighboring gene uncharacterized protein Neighboring gene mutagen-sensitive 312 Neighboring gene wurmchen 1 Neighboring gene wurmchen 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion. Valoskova K, et al. Elife, 2019 Mar 26. PMID 30910009, Free PMC Article
  2. Glucose Availability Alters Gene and Protein Expression of Several Newly Classified and Putative Solute Carriers in Mice Cortex Cell Culture and D. melanogaster. Ceder MM, et al. Front Cell Dev Biol, 2020. PMID 32733888, Free PMC Article
  3. The Identification and Evolutionary Trends of the Solute Carrier Superfamily in Arthropods. Denecke SM, et al. Genome Biol Evol, 2020 Aug 1. PMID 32681801, Free PMC Article
  4. Identification of Genes Involved in the Differentiation of R7y and R7p Photoreceptor Cells in Drosophila. Earl JB, et al. G3 (Bethesda), 2020 Nov 5. PMID 32972998, Free PMC Article
  5. Retroposed new genes out of the X in Drosophila. Betrán E, et al. Genome Res, 2002 Dec. PMID 12466289, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in Golgi membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in endosome IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
minerva
Names
CG8602-PA
CG8602-PB
mrva-PA
mrva-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    7326273..7328842 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139846.3 → NP_648103.1  minerva, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648103.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VS47
    Related
    FBpp0076594
    Conserved Domains (2) summary
    cd06174
    Location:55 → 448
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:58 → 410
    MFS_1; Major Facilitator Superfamily

  2. NM_001274576.1 → NP_001261505.1  minerva, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261505.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VS47
    Conserved Domains (2) summary
    cd06174
    Location:55 → 448
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:58 → 410
    MFS_1; Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VS47 Q9VS47

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