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Acbp3 Acyl-CoA binding protein 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38783, updated on 9-Dec-2024

Summary

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Official Symbol
Acbp3provided by FlyBase
Official Full Name
Acyl-CoA binding protein 3provided by FlyBase
Primary source
FLYBASE:FBgn0250836
Locus tag
Dmel_CG8628
See related
AllianceGenome:FB:FBgn0250836
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
ACBP; anon-SAGE:Wang-073; CG8628; DmCG8628; Dmel\CG8628
Summary
Predicted to enable long-chain fatty acyl-CoA binding activity. Predicted to be involved in fatty acid metabolic process. Orthologous to human ACBD7 (acyl-CoA binding domain containing 7) and DBI (diazepam binding inhibitor, acyl-CoA binding protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Acbp3 in Genome Data Viewer
Location:
65E4-65E4; 3-19 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7130874..7131505)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7123974..7124605)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Bardet-Biedl syndrome 1 Neighboring gene Acyl-CoA binding protein 4 Neighboring gene Acyl-CoA binding protein 6 Neighboring gene Acyl-CoA binding protein 2 Neighboring gene melted Neighboring gene cornetto

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The ACBP gene family in Rhodnius prolixus: Expression, characterization and function of RpACBP-1. Majerowicz D, et al. Insect Biochem Mol Biol, 2016 May. PMID 27001070
  2. The microbiome stabilizes circadian rhythms in the gut. Zhang Y, et al. Proc Natl Acad Sci U S A, 2023 Jan 31. PMID 36689661, Free PMC Article
  3. Regulatory regions in natural transposable element insertions drive interindividual differences in response to immune challenges in Drosophila. Ullastres A, et al. Genome Biol, 2021 Sep 14. PMID 34521452, Free PMC Article
  4. Stress response, behavior, and development are shaped by transposable element-induced mutations in Drosophila. Rech GE, et al. PLoS Genet, 2019 Feb. PMID 30753202, Free PMC Article
  5. A distinct Acyl-CoA binding protein (ACBP6) shapes tissue plasticity during nutrient adaptation in Drosophila. Li X, et al. Nat Commun, 2023 Nov 21. PMID 37989752, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables fatty-acyl-CoA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables fatty-acyl-CoA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Acyl-CoA binding protein 3
Names
Acbp3-PA
Acbp3-PB
CG8628-PA
CG8628-PB
acyl-CoA-binding protein
anon-SAGE:Wang-073

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    7130874..7131505
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139826.3 → NP_648083.1  Acyl-CoA binding protein 3, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648083.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3LF68, Q9VS22
    Related
    FBpp0076623
    Conserved Domains (1) summary
    cl00221
    Location:4 → 84
    ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...

  2. NM_001169895.1 → NP_001163366.1  Acyl-CoA binding protein 3, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163366.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3LF68, Q9VS22
    Conserved Domains (1) summary
    cl00221
    Location:4 → 84
    ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VS22 Q9VS22

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