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msl-3 - male-specific lethal 3

Enables several functions, including histone reader activity; lncRNA binding activity; and methylated histone binding activity. Involved in dosage compensation by hyperactivation of X chromosome; oocyte development; and regulation of hemocyte proliferation. Located in chromocenter and chromosome. Part of MSL complex and X chromosome located dosage compensation complex, transcription activating. Is expressed in organism. Human ortholog(s) of this gene implicated in Basilicata-Akhtar syndrome. Orthologous to several human genes including MSL3 (MSL complex subunit 3). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa