tow - target of wingless

Involved in establishment of planar polarity; imaginal disc-derived wing hair organization; and negative regulation of smoothened signaling pathway. Located in nucleus. Is expressed in several structures, including adult head; ganglia; larval nervous system; and wing disc. Orthologous to human C1orf21 (chromosome 1 open reading frame 21). [provided by Alliance of Genome Resources, Dec 2024]