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SP1173 SP1173 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38744, updated on 9-Dec-2024

Summary

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Official Symbol
SP1173provided by FlyBase
Official Full Name
SP1173provided by FlyBase
Primary source
FLYBASE:FBgn0035710
Locus tag
Dmel_CG10121
See related
AllianceGenome:FB:FBgn0035710
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10121; Dmel\CG10121
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Is expressed in several structures, including adult head; central brain primordium; embryonic stomatogastric nervous system; ganglia; and larval muscle cell. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See SP1173 in Genome Data Viewer
Location:
65C1-65C3; 3-17 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6689327..6703521, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6682427..6696621, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45173 Neighboring gene Gustatory receptor-like 65a Neighboring gene uncharacterized protein Neighboring gene pale

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Hox proteins Ubx and AbdA collaborate with the transcription pausing factor M1BP to regulate gene transcription. Zouaz A, et al. EMBO J, 2017 Oct 2. PMID 28871058, Free PMC Article
  2. dTcf/Pangolin suppresses growth and tumor formation in Drosophila. Song S, et al. Proc Natl Acad Sci U S A, 2019 Jul 9. PMID 31235567, Free PMC Article
  3. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Hollien J, et al. Science, 2006 Jul 7. PMID 16825573
  4. Automatic image analysis for gene expression patterns of fly embryos. Peng H, et al. BMC Cell Biol, 2007 Jul 10. PMID 17634097, Free PMC Article
  5. Male-specific fruitless isoforms target neurodevelopmental genes to specify a sexually dimorphic nervous system. Neville MC, et al. Curr Biol, 2014 Feb 3. PMID 24440396, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
SP1173
Names
CG10121-PA
CG10121-PB
CG10121-PC
CG10121-PD
SP1173-PA
SP1173-PB
SP1173-PC
SP1173-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    6689327..6703521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168177.3 → NP_729184.1  SP1173, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_729184.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E8H7, Q8MQS1, Q9NGV3
    Related
    FBpp0076667
    Conserved Domains (2) summary
    cl17781
    Location:552 → 632
    Chromate_transp; Chromate transporter
    cl21472
    Location:15 → 88
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

  2. NM_168178.2 → NP_729185.1  SP1173, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_729185.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E8H7, Q8MQS1, Q9NGV3
    Related
    FBpp0076668
    Conserved Domains (2) summary
    cl17781
    Location:552 → 632
    Chromate_transp; Chromate transporter
    cl21472
    Location:15 → 88
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

  3. NM_139796.3 → NP_648053.1  SP1173, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648053.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E8H7, Q8MQS1, Q9NGV3
    Related
    FBpp0076670
    Conserved Domains (2) summary
    cl17781
    Location:552 → 632
    Chromate_transp; Chromate transporter
    cl21472
    Location:15 → 88
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

  4. NM_168176.2 → NP_729183.1  SP1173, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_729183.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E8H7, Q8MQS1, Q9NGV3
    Related
    FBpp0076669
    Conserved Domains (2) summary
    cl17781
    Location:552 → 632
    Chromate_transp; Chromate transporter
    cl21472
    Location:15 → 88
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0E8H7 Q0E8H7
Q8MQS1 Q8MQS1
Q9NGV3 Q9NGV3

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