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CG10467 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38697, updated on 4-Jan-2025

Summary

Official Symbol
CG10467provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035679
Locus tag
Dmel_CG10467
See related
AllianceGenome:FB:FBgn0035679
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10467
Summary
Predicted to enable aldose 1-epimerase activity. Predicted to be involved in galactose catabolic process via UDP-galactose and glucose metabolic process. Located in extracellular region. Is expressed in several structures, including adult heart; anterior endoderm; anterior endoderm anlage; embryonic/larval crystal cell; and embryonic/larval midgut primordium. Human ortholog(s) of this gene implicated in galactosemia 4. Orthologous to human GALM (galactose mutarotase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See CG10467 in Genome Data Viewer
Location:
65A6-65A6; 3-16 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6093204..6094747, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6086304..6087847, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene short spindle 6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene logjam Neighboring gene Ets at 65A Neighboring gene long non-coding RNA:CR46001

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables aldose 1-epimerase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables aldose 1-epimerase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in galactose catabolic process via UDP-galactose IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in galactose catabolic process via UDP-galactose ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in glucose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in hexose metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in extracellular region HDA PubMed 

General protein information

Preferred Names
uncharacterized protein
Names
CG10467-PA
NP_648026.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    6093204..6094747 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139769.2NP_648026.1  uncharacterized protein Dmel_CG10467 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648026.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MT28, Q9VRU1
    Related
    FBpp0076771
    Conserved Domains (1) summary
    cd09019
    Location:26360
    galactose_mutarotase_like; galactose mutarotase_like