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ssp6 short spindle 6 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38694, updated on 9-Dec-2024

Summary

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Official Symbol
ssp6provided by FlyBase
Official Full Name
short spindle 6provided by FlyBase
Primary source
FLYBASE:FBgn0035676
Locus tag
Dmel_CG6619
See related
AllianceGenome:FB:FBgn0035676
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6619; Dmel\CG6619; Ssp6
Summary
Is expressed in adult head; embryonic brain; embryonic/larval oenocyte; embryonic/larval visceral tracheal branch; and larval ventral nerve cord. Orthologous to several human genes including CYTIP (cytohesin 1 interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See ssp6 in Genome Data Viewer
Location:
65A5-65A5; 3-16 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6076722..6082491)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6069822..6075591)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells. Moutinho-Pereira S, et al. Proc Natl Acad Sci U S A, 2013 Dec 3. PMID 24255106, Free PMC Article
  2. Genome-wide analysis in Drosophila reveals diet-by-gene interactions and uncovers diet-responsive genes. Francis D, et al. G3 (Bethesda), 2021 Sep 27. PMID 34568906, Free PMC Article
  3. Neurological proteins are not enriched for repetitive sequences. Huntley MA, et al. Genetics, 2004 Mar. PMID 15082536, Free PMC Article
  4. The genetic architecture of odor-guided behavior in Drosophila melanogaster. Anholt RR, et al. Behav Genet, 2001 Jan. PMID 11529271
  5. Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. Brody T, et al. Mech Dev, 2002 Apr. PMID 11900973

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
short spindle 6
Names
CG6619-PA
CG6619-PB
ssp6-PA
ssp6-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    6076722..6082491
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300023.1 → NP_001286952.1  short spindle 6, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286952.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SXG1, Q9VRT8
    Conserved Domains (1) summary
    cd00992
    Location:130 → 216
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  2. NM_139766.2 → NP_648023.2  short spindle 6, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648023.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SXG1, Q9VRT8
    Related
    FBpp0076757
    Conserved Domains (1) summary
    cd00992
    Location:130 → 216
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SXG1 Q8SXG1
Q9VRT8 Q9VRT8

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