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Bre1 - Bre1

Enables ubiquitin protein ligase activity. Involved in chromatin organization; positive regulation of macromolecule biosynthetic process; and protein monoubiquitination. Located in nucleus. Used to study congenital heart disease. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to several human genes including RNF40 (ring finger protein 40). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

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Species Gene Architecture aa