U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

spo spook [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38631, updated on 9-Dec-2024

Summary

Official Symbol
spoprovided by FlyBase
Official Full Name
spookprovided by FlyBase
Primary source
FLYBASE:FBgn0003486
Locus tag
Dmel_CG10594
See related
AllianceGenome:FB:FBgn0003486
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
307a1; CG10594; Cyp307a1; CYP307A1; CYP307A1-Dm; Dmel\CG10594; Dmspo; Spo
Summary
Predicted to enable heme binding activity and oxidoreductase activity. Involved in several processes, including digestive tract development; ecdysone biosynthetic process; and embryonic development via the syncytial blastoderm. Located in endoplasmic reticulum. Is expressed in several structures, including amnioserosa; amnioserosa primordium; follicle cell; yolk; and yolk nucleus. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See spo in Genome Data Viewer
Location:
64D5-64D5; 3-14 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (5590083..5592571, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (5583183..5585671, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene bc10 Neighboring gene small non-coding RNA 357 Neighboring gene Msr-110 Neighboring gene lethal (3) persistent salivary gland 2 Neighboring gene Alkaline phosphatase 10 Neighboring gene Alkaline phosphatase 9

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 
enables heme binding ISM
Inferred from Sequence Model
more info
PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity ISM
Inferred from Sequence Model
more info
PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in central nervous system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cuticle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in dorsal closure IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ecdysone biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in embryonic development via the syncytial blastoderm IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in embryonic digestive tract development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in head involution IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in midgut development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in oogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
spook
Names
CG10594-PA
CG10594-PC
spo-PA
spo-PC
NP_001286943.1
NP_647975.2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    5590083..5592571 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300014.1NP_001286943.1  spook, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286943.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8SZ84, Q9VRM7
    UniProtKB/TrEMBL
    H8F4V5
    Conserved Domains (1) summary
    cl12078
    Location:56540
    p450; Cytochrome P450
  2. NM_139718.3NP_647975.2  spook, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647975.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8SZ84, Q9VRM7
    UniProtKB/TrEMBL
    H8F4V5
    Related
    FBpp0076836
    Conserved Domains (1) summary
    cl12078
    Location:56540
    p450; Cytochrome P450