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CG11342 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38538, updated on 9-Dec-2024

Summary

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Official Symbol
CG11342provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035537
Locus tag
Dmel_CG11342
See related
AllianceGenome:FB:FBgn0035537
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG11342
Summary
Predicted to enable O-methyltransferase activity and RNA methyltransferase activity. Predicted to be involved in negative regulation of pre-miRNA processing. Predicted to be active in cytoplasm. Orthologous to human BCDIN3D (BCDIN3 domain containing RNA methyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG11342 in Genome Data Viewer
Location:
64B2-64B2; 3-12 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4366494..4367458, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4366494..4367458, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Cdc42-interacting protein 4 Neighboring gene long non-coding RNA:CR45156 Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein S6 Neighboring gene Dopamine/Ecdysteroid receptor Neighboring gene long non-coding RNA:CR44360 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila Amus and Bin3 methylases functionally replace mammalian MePCE for capping and the stabilization of U6 and 7SK snRNAs. Peng Q, et al. Sci Adv, 2023 Dec 15. PMID 38100593, Free PMC Article
  2. Automated identification of putative methyltransferases from genomic open reading frames. Katz JE, et al. Mol Cell Proteomics, 2003 Aug. PMID 12872006
  3. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
  4. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article
  5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables O-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of pre-miRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11342-PA
NP_647896.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    4366494..4367458 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139639.2 → NP_647896.1  uncharacterized protein Dmel_CG11342 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647896.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VZD2
    UniProtKB/TrEMBL
    N0D4J1
    Related
    FBpp0073194
    Conserved Domains (2) summary
    pfam08242
    Location:56 → 165
    Methyltransf_12; Methyltransferase domain
    cl17173
    Location:134 → 238
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VZD2.1 Q9VZD2

Gene LinkOut

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