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Cpr64Aa Cuticular protein 64Aa [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38508, updated on 9-Dec-2024

Summary

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Official Symbol
Cpr64Aaprovided by FlyBase
Official Full Name
Cuticular protein 64Aaprovided by FlyBase
Primary source
FLYBASE:FBgn0035510
Locus tag
Dmel_CG15006
See related
AllianceGenome:FB:FBgn0035510
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15006; DmelCpr64Aa; Dmel\CG15006
Summary
Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be located in chitin-based extracellular matrix. Predicted to be active in extracellular matrix. Is expressed in adult head and organism. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Cpr64Aa in Genome Data Viewer
Location:
64A10-64A10; 3-10 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4207838..4209178, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4207838..4209178, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene temperature-induced paralytic E Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 64Ab Neighboring gene Cuticular protein 64Ac

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Proteome response to the panneural expression of human wild-type alpha-synuclein: a Drosophila model of Parkinson's disease. Xun Z, et al. J Proteome Res, 2008 Sep. PMID 18683964, Free PMC Article
  2. Quantitative proteomics of a presymptomatic A53T alpha-synuclein Drosophila model of Parkinson disease. Xun Z, et al. Mol Cell Proteomics, 2008 Jul. PMID 18353766, Free PMC Article
  3. A Drosophila model of the neurodegenerative disease SCA17 reveals a role of RBP-J/Su(H) in modulating the pathological outcome. Ren J, et al. Hum Mol Genet, 2011 Sep 1. PMID 21653638, Free PMC Article
  4. Extensive gene amplification and concerted evolution within the CPR family of cuticular proteins in mosquitoes. Cornman RS, et al. Insect Biochem Mol Biol, 2008 Jun. PMID 18510978, Free PMC Article
  5. Regulators of Long-Term Memory Revealed by Mushroom Body-Specific Gene Expression Profiling in Drosophila melanogaster. Widmer YF, et al. Genetics, 2018 Aug. PMID 29925565, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of chitin-based larval cuticle ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in chitin-based cuticle development ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
located_in chitin-based extracellular matrix ISM
Inferred from Sequence Model
more info
 PubMed 
is_active_in extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cuticular protein 64Aa
Names
CG15006-PA
Cpr64Aa-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    4207838..4209178 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139615.3 → NP_647872.1  cuticular protein 64Aa [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647872.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VZG2
    Related
    FBpp0073110
    Conserved Domains (1) summary
    pfam00379
    Location:60 → 112
    Chitin_bind_4; Insect cuticle protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VZG2 Q9VZG2

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