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VhaM9.7-c Vacuolar H[+] ATPase M9.7 subunit c [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38503, updated on 9-Dec-2024

Summary

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Official Symbol
VhaM9.7-cprovided by FlyBase
Official Full Name
Vacuolar H[+] ATPase M9.7 subunit cprovided by FlyBase
Primary source
FLYBASE:FBgn0028664
Locus tag
Dmel_CG11589
See related
AllianceGenome:FB:FBgn0028664
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11589; Dmel\CG11589; vhaM9.2-1; vhaM9.7-1; VhaM9.7-1; vhaM9.7-3; VhaM9.7-3
Summary
Predicted to contribute to proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to be part of plasma membrane proton-transporting V-type ATPase complex and vacuolar proton-transporting V-type ATPase, V0 domain. Is expressed in adult heart and organism. Orthologous to several human genes including ATP6V0E2 (ATPase H+ transporting V0 subunit e2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See VhaM9.7-c in Genome Data Viewer
Location:
64A10-64A10; 3-10 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4186018..4186865, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4186018..4186865, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene tipE homolog 4 Neighboring gene tipE homolog 2 Neighboring gene tipE homolog 3 Neighboring gene temperature-induced paralytic E Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Four novel sequences in Drosophila melanogaster homologous to the auxiliary Para sodium channel subunit TipE. Derst C, et al. Biochem Biophys Res Commun, 2006 Jan 20. PMID 16325765
  2. The multifunctional Drosophila melanogaster V-ATPase is encoded by a multigene family. Dow JA. J Bioenerg Biomembr, 1999 Feb. PMID 10340851
  3. Transcriptional responses to hyperplastic MRL signalling in Drosophila. Jonchère V, et al. Open Biol, 2017 Feb. PMID 28148822, Free PMC Article
  4. Genome-wide survey of V-ATPase genes in Drosophila reveals a conserved renal phenotype for lethal alleles. Allan AK, et al. Physiol Genomics, 2005 Jul 14. PMID 15855386
  5. Genome-wide identification of mRNAs associated with the translational regulator PUMILIO in Drosophila melanogaster. Gerber AP, et al. Proc Natl Acad Sci U S A, 2006 Mar 21. PMID 16537387, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables proton-transporting ATPase activity, rotational mechanism IEA
Inferred from Electronic Annotation
more info
  
contributes_to proton-transporting ATPase activity, rotational mechanism ISM
Inferred from Sequence Model
more info
  
Process Evidence Code Pubs
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in proton transmembrane transport ISM
Inferred from Sequence Model
more info
  
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of plasma membrane proton-transporting V-type ATPase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of proton-transporting V-type ATPase, V0 domain IEA
Inferred from Electronic Annotation
more info
  
part_of vacuolar proton-transporting V-type ATPase, V0 domain ISM
Inferred from Sequence Model
more info
  
part_of vacuolar proton-transporting V-type ATPase, V0 domain ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
vacuolar H[+] ATPase M9.7 subunit c
Names
CG11589-PA
VhaM9.7-1
VhaM9.7-c-PA
vacuolar H[+] ATPase subunit M9.7-c

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    4186018..4186865 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139611.3 → NP_647868.1  vacuolar H[+] ATPase M9.7 subunit c [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647868.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VZG7
    Related
    FBpp0073112
    Conserved Domains (1) summary
    pfam05493
    Location:6 → 64
    ATP_synt_H; ATP synthase subunit H
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VZG7 Q9VZG7

Gene LinkOut

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