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Fit1 - Fermitin 1

Predicted to enable integrin binding activity. Involved in cardiac muscle tissue development and defense response to Gram-negative bacterium. Predicted to be located in cytoplasm. Predicted to be active in cell-substrate junction. Is expressed in adult head; adult heart; and organism. Human ortholog(s) of this gene implicated in Kindler syndrome; leukocyte adhesion deficiency 1; leukocyte adhesion deficiency 3; telangiectasis; and vesiculobullous skin disease. Orthologous to several human genes including FERMT1 (FERM domain containing kindlin 1) and FERMT2 (FERM domain containing kindlin 2). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa