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CG32262 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38445, updated on 9-Dec-2024

Summary

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Official Symbol
CG32262provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0052262
Locus tag
Dmel_CG32262
See related
AllianceGenome:FB:FBgn0052262
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10854; Dmel\CG32262
Summary
Predicted to enable monoatomic ion channel activity. Predicted to be involved in mitochondrial ribosome assembly and monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Orthologous to human MPV17L2 (MPV17 mitochondrial inner membrane protein like 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG32262 in Genome Data Viewer
Location:
63F1-63F1; 3-9 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3809146..3810196, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3809146..3810196, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Integrator 10 Neighboring gene nutcracker Neighboring gene uncharacterized protein Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Drosophila model of the neurological symptoms in Mpv17-related diseases. Kodani A, et al. Sci Rep, 2022 Dec 31. PMID 36587049, Free PMC Article
  2. Drosophila Mpv17 forms an ion channel and regulates energy metabolism. Corrà S, et al. iScience, 2023 Oct 20. PMID 37810222, Free PMC Article
  3. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273
  4. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article
  5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables monoatomic ion channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in mitochondrial ribosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in monoatomic ion transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial inner membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG32262-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    3809146..3810196 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139574.4 → NP_647831.1  uncharacterized protein Dmel_CG32262 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647831.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T0R4, Q9VZM6
    Related
    FBpp0073040
    Conserved Domains (1) summary
    pfam04117
    Location:175 → 238
    Mpv17_PMP22; Mpv17 / PMP22 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VZM6 Q9VZM6

Gene LinkOut

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