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CG10359 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38434, updated on 4-Jan-2025

Summary

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Official Symbol
CG10359provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035452
Locus tag
Dmel_CG10359
See related
AllianceGenome:FB:FBgn0035452
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AAF47782; Dmel\CG10359; FBpp0072995
Summary
Predicted to enable G protein-coupled receptor binding activity and chitin binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including dorsal head epidermis; embryonic hypopharynx; embryonic salivary gland duct; ganglia; and larval glial cell. Orthologous to human TNR (tenascin R). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG10359 in Genome Data Viewer
Location:
63E5-63E5; 3-8 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3612192..3615244)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3612192..3615244)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Ecdysone-induced protein 63E Neighboring gene long non-coding RNA:CR45820 Neighboring gene small nuclear RNA U7 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparison of embryonic expression within multigene families using the FlyExpress discovery platform reveals more spatial than temporal divergence. Konikoff CE, et al. Dev Dyn, 2012 Jan. PMID 21960044, Free PMC Article
  2. Dying cells protect survivors from radiation-induced cell death in Drosophila. Bilak A, et al. PLoS Genet, 2014 Mar. PMID 24675716, Free PMC Article
  3. Identification and characterization of the fibrinogen-like domain of fibrinogen-related proteins in the mosquito, Anopheles gambiae, and the fruitfly, Drosophila melanogaster, genomes. Wang X, et al. BMC Genomics, 2005 Sep 8. PMID 16150145, Free PMC Article
  4. Evolution and potential function of fibrinogen-like domains across twelve Drosophila species. Middha S, et al. BMC Genomics, 2008 May 30. PMID 18513432, Free PMC Article
  5. Microarray analysis of replicate populations selected against a wing-shape correlation in Drosophila melanogaster. Weber KE, et al. Genetics, 2008 Feb. PMID 18245369, Free PMC Article

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables G protein-coupled receptor binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables chitin binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in collagen-containing extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10359-PE
CG10359-PG
Fibrinogen-related protein
Fibronogen-like

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    3612192..3615244
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001144410.2 → NP_001137882.1  uncharacterized protein Dmel_CG10359, isoform E [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z0B2, Q8SYI4, Q9VZN7
    Conserved Domains (1) summary
    cd00087
    Location:267 → 476
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...

  2. NM_001144409.2 → NP_001137881.1  uncharacterized protein Dmel_CG10359, isoform G [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z0B3, Q8SYI4, Q9VZN7
    Conserved Domains (1) summary
    cd00087
    Location:241 → 450
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B7Z0B2 B7Z0B2
B7Z0B3 B7Z0B3
Q95S38 Q95S38
Q9VZN7 Q9VZN7

Gene LinkOut

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