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Drsl2 Drosomycin-like 2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38408, updated on 9-Dec-2024

Summary

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Official Symbol
Drsl2provided by FlyBase
Official Full Name
Drosomycin-like 2provided by FlyBase
Primary source
FLYBASE:FBgn0052279
Locus tag
Dmel_CG32279
See related
AllianceGenome:FB:FBgn0052279
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10813; CG32279; CT30310; Dmel\CG32279; dmy2; dro-2; Dro-D; dro2; Dro2; Drs-lD; drsl2
Summary
Involved in defense response to fungus and defense response to protozoan. Predicted to be located in extracellular region. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Drsl2 in Genome Data Viewer
Location:
63D1-63D1; 3-8 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3314349..3314681)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3314349..3314681)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Zinc transporter 63C Neighboring gene Drosomycin-like 3 Neighboring gene Drosomycin-like 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Upregulation of genes belonging to the drosomycin family in diapausing adults of Drosophila triauraria. Daibo S, et al. Gene, 2001 Oct 31. PMID 11707335
  2. Functional role of charged residues in drosomycin, a Drosophila antifungal peptide. Zhang Z, et al. Dev Comp Immunol, 2010 Sep. PMID 20420852
  3. Functional divergence of six isoforms of antifungal peptide Drosomycin in Drosophila melanogaster. Yang WY, et al. Gene, 2006 Sep 1. PMID 16824706
  4. Gene expression, antiparasitic activity, and functional evolution of the drosomycin family. Tian C, et al. Mol Immunol, 2008 Sep. PMID 18657321
  5. Gene expression divergence and evolutionary analysis of the drosomycin gene family in Drosophila melanogaster. Deng XJ, et al. J Biomed Biotechnol, 2009. PMID 19888430, Free PMC Article

See all (57) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Co-option of immune effectors by the hormonal signalling system triggering metamorphosis in Drosophila melanogaster.
    Title: Co-option of immune effectors by the hormonal signalling system triggering metamorphosis in Drosophila melanogaster.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in defense response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in defense response IEA
Inferred from Electronic Annotation
more info
  
involved_in defense response to fungus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in defense response to fungus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in defense response to protozoan IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
 PubMed 
located_in extracellular region ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
Drosomycin-like 2
Names
CG32279-PA
Drosomycin-like D
Drsl2-PA
drosomycin
drosomycin 2
drosomycin-2
drosomycin-D

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    3314349..3314681
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168019.4 → NP_728860.2  Drosomycin-like 2 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728860.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2UYB4, Q7YXH9, Q9VZR3
    Conserved Domains (1) summary
    pfam00304
    Location:27 → 69
    Gamma-thionin; Gamma-thionin family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2UYB4 Q2UYB4
Q7YXH9 Q7YXH9

Gene LinkOut

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